AHR

aryl hydrocarbon receptor

Summary

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]

Known Variants406 total

rsidPosition (GRCh37)AllelesClassClinVar
rs44107907:17,284,577T/Cintron variant—
rs102497887:17,338,147C/Tregulatory region variant—
rs25344008947:17,338,889A/G—uncertain significance
rs17819283457:17,338,895A/G—uncertain significance
rs12780626937:17,338,896G/C—uncertain significance
rs25344009497:17,338,907A/G—uncertain significance
rs13581810247:17,338,908A/G—uncertain significance
rs2013687377:17,338,923G/A—uncertain significance
rs9515500407:17,338,926G/T—uncertain significance
rs12176285047:17,338,939G/A—likely benign
rs5308940637:17,338,952A/T—uncertain significance
rs7535554637:17,338,967G/A—likely benign
rs9415939007:17,338,970C/T—likely benign
rs22828857:17,345,614A/Gintron variant—
rs13069832777:17,349,547G/A—likely benign
rs11989863387:17,349,568C/A—uncertain significance
rs21153529747:17,349,569A/C—likely benign
rs8682512847:17,349,598C/T—uncertain significance
rs3688188417:17,349,602C/G—likely benign
rs3713217917:17,349,605G/A—likely benign
rs7485457887:17,349,606C/A—likely benign
rs7730417107:17,349,608G/A—likely benign
rs10333566877:17,349,618C/A—likely benign
rs177793527:17,349,626C/T—benign
rs17820459207:17,349,628C/T—uncertain significance
rs7658548527:17,349,639C/T—uncertain significance
rs3748272937:17,349,640G/A—uncertain significance
rs412730547:17,349,644G/A—likely benign
rs9048533607:17,349,663C/G—uncertain significance
rs1424121997:17,349,691A/G—uncertain significance
rs7677193607:17,349,698A/G—likely benign
rs21153530277:17,349,699G/A—uncertain significance
rs7563066657:17,349,707G/A—likely benign
rs7612360077:17,349,713C/T—likely benign
rs5457822087:17,349,714G/A—uncertain significance
rs3772945957:17,349,733A/G—uncertain significance
rs25344133317:17,349,752G/A—uncertain significance
rs25344133387:17,349,755A/G—likely benign
rs17820474037:17,349,764T/C—likely benign
rs1176451687:17,349,765A/G—likely benign
rs3696453857:17,349,766A/G—likely benign
rs14760807:17,357,873T/A——
rs22372977:17,359,594G/Aintron variant—
rs171375667:17,360,521T/G——
rs21153594017:17,362,113T/G—likely benign
rs25344266447:17,362,128C/T—uncertain significance
rs1415189847:17,362,129A/G—likely benign
rs7749927297:17,362,140C/T—uncertain significance
rs7628135617:17,362,141C/T—likely benign
rs1901388577:17,362,142C/A—uncertain significance
rs17821849457:17,362,149A/G—uncertain significance
rs11874940367:17,362,150A/G—likely benign
rs21153594407:17,362,154A/G—uncertain significance
rs7615663177:17,362,156C/T—likely benign
rs7665922047:17,362,157G/A—uncertain significance
rs7744065367:17,362,167A/T—uncertain significance
rs15624782467:17,362,174T/C—likely benign
rs2003244937:17,362,175A/G—uncertain significance
rs5702828327:17,362,178G/A—uncertain significance
rs3777243967:17,362,183A/C—likely benign
rs1509119497:17,362,191G/T—uncertain significance
rs13420810267:17,362,195A/T—uncertain significance
rs1994981927:17,362,197G/T—uncertain significance
rs25344267787:17,362,200T/G—uncertain significance
rs7795011197:17,362,207A/G—likely benign
rs3747914707:17,362,210A/T—uncertain significance
rs7686202427:17,362,221T/A—uncertain significance
rs7741957387:17,362,226T/C—likely benign
rs21153595207:17,362,244A/G—likely benign
rs7597905777:17,362,247T/C—likely benign
rs2022040217:17,367,365A/G—likely benign
rs17822442907:17,367,375C/A—likely benign
rs2016282527:17,367,379G/A—likely benign
rs1416671127:17,367,414C/T—uncertain significance
rs21153625817:17,367,420C/A—uncertain significance
rs12889668497:17,367,441C/G—uncertain significance
rs1438483527:17,367,443A/T—uncertain significance
rs15840380057:17,367,450A/G—uncertain significance
rs13561594547:17,367,456A/G—uncertain significance
rs12409032707:17,367,458C/G—uncertain significance
rs7546743907:17,367,476A/G—uncertain significance
rs11986495387:17,367,479A/G—likely benign
rs69601657:17,368,085G/T——
rs21580417:17,368,420T/A——
rs7666729377:17,369,557T/C—likely benign
rs1504956437:17,369,558T/C—likely benign
rs7649875787:17,369,559G/A—likely benign
rs9080536297:17,369,577C/A—uncertain significance
rs21153640047:17,369,582G/A—uncertain significance
rs21153640097:17,369,593G/C—uncertain significance
rs25344351797:17,369,595G/A—uncertain significance
rs21153640117:17,369,596T/C—likely benign
rs25344352047:17,369,608T/C—likely benign
rs7456965627:17,369,618G/A—uncertain significance
rs9421384587:17,369,639C/T—uncertain significance
rs7721973527:17,369,640G/A—uncertain significance
rs17822703007:17,369,650C/G—uncertain significance
rs3686150717:17,369,660A/C—uncertain significance
rs7768360107:17,369,669C/G—uncertain significance
rs21153640767:17,369,672T/C—uncertain significance

Showing 100 of 406 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.