rs11508026

This is a regulatory region variant variant in the CETP gene.

GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Research that mentions this SNP (1)

Use of longitudinal data in genetic studies in the genome‐wide association studies era: summary of Group 14
ReviewN=14,658Kerner B. et al.(2009)· Genetic Epidemiology

This is a summary of Group 14 analyses from the Genetic Analysis Workshop 16 (GAW16) demonstrating the use of longitudinal data from the Framingham Heart Study in genome-wide association studies. Multiple analytical approaches were compared for identifying genetic associations with metabolic and cardiovascular traits including BMI, type 2 diabetes, blood pressure, lipid levels, and coronary heart disease, using various statistical methods such as linear mixed models, growth mixture modeling, and generalized estimating equations.

Traits studied:Body Mass IndexCoronary Artery CalcificationCoronary Heart DiseaseHigh-Density LipoproteinLow-Density LipoproteinMetabolic SyndromeSystolic Blood PressureTriglyceridesType 2 DiabetesWeight

About CETP

The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

View all CETP variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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