rs11724758
This is a 3 prime utr variant variant in the FABP2 gene.
▶Research that mentions this SNP (1)
▶Single nucleotide polymorphism associated with nonsyndromic cleft palate influences the processing of miR‐140AssociationN=116Ling Li et al.(2010)· American Journal of Medical Genetics Part A
This case-control study of 57 children/adolescents with metabolic syndrome (MetS) and 59 controls examined five SNPs in the APOA5 gene's miRNA target sites. Only rs72525532 (c.*285_*286insGA) showed variation, with the AA insertion genotype significantly more frequent in MetS cases (12.28%) versus controls (1.7%, P=0.012) and associated with increased triglycerides and MetS risk (OR=8.12, P=0.05), though this association became non-significant after age adjustment (OR=5.66, P=0.124).
About FABP2
The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017]
View all FABP2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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