AAMP
angio associated migratory cell protein
Summary
The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2469244586 | 2:219,130,374 | G/A | — | uncertain significance |
| rs1079204 | 2:219,130,514 | G/A | upstream gene variant | — |
| rs750363698 | 2:219,130,567 | G/A | — | uncertain significance |
| rs1023811371 | 2:219,131,210 | T/G | — | uncertain significance |
| rs1262411187 | 2:219,131,213 | A/C | — | uncertain significance |
| rs367763639 | 2:219,131,270 | C/G | — | uncertain significance |
| rs1366028725 | 2:219,131,302 | C/G | — | uncertain significance |
| rs138058625 | 2:219,131,623 | A/T | — | uncertain significance |
| rs1373968697 | 2:219,132,244 | C/T | — | uncertain significance |
| rs1690663349 | 2:219,132,264 | G/C | — | uncertain significance |
| rs4674279 | 2:219,132,731 | G/A | upstream gene variant | — |
| rs181306123 | 2:219,134,168 | C/T | — | uncertain significance |
| rs141356609 | 2:219,134,221 | T/C | — | uncertain significance |
| rs867936162 | 2:219,134,238 | C/T | — | uncertain significance |
| rs150307616 | 2:219,134,752 | T/C | — | uncertain significance |
| rs368777489 | 2:219,134,766 | G/T | — | uncertain significance |
| rs145888617 | 2:219,134,767 | G/T | — | uncertain significance |
| rs121434512 | 2:219,135,278 | C/T | missense variant | pathogenic |
| rs121434511 | 2:219,135,284 | C/T | missense variant | pathogenic |
| rs121434513 | 2:219,136,133 | G/C | missense variant | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.