Guides

Practical, sourced guides to getting real information out of your raw DNA data.

• Promethease alternatives in 2026: where to analyze raw DNA now

  Promethease no longer stores data and SNPedia hasn't been updated since 2019. Here are the current options for analyzing 23andMe, AncestryDNA, and WGS raw data.

  August 9, 2026

• Polygenic risk scores from raw DNA: what they can and can't tell you

  How polygenic risk scores work, why ancestry calibration matters, what a percentile actually means, and the honest limitations of computing PRS from chip data.

  August 9, 2026

• How to download your raw DNA data from 23andMe and AncestryDNA

  Step-by-step instructions for exporting your raw genotype file from 23andMe and AncestryDNA, what the file contains, and why you should keep a copy.

  August 9, 2026

• How to analyze your 23andMe raw data (2026 guide)

  A practical guide to getting real information out of your 23andMe or AncestryDNA raw data file: traits, pharmacogenomics, ClinVar variants, and polygenic risk scores.

  August 9, 2026