ABRA
actin binding Rho activating protein
Summary
Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization; positive regulation of Rho protein signal transduction; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of DNA-templated transcription and protein import into nucleus. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants39 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs200631708 | 8:107,773,278 | G/A | — | uncertain significance |
| rs111803056 | 8:107,773,280 | A/C | — | uncertain significance |
| rs765786301 | 8:107,773,300 | G/C | — | uncertain significance |
| rs34165567 | 8:107,773,303 | C/T | — | uncertain significance |
| rs372554852 | 8:107,773,348 | T/C | — | uncertain significance |
| rs1015238596 | 8:107,773,366 | C/T | — | uncertain significance |
| rs375791517 | 8:107,773,386 | C/T | — | uncertain significance |
| rs370150080 | 8:107,773,387 | G/A | — | uncertain significance |
| rs190134757 | 8:107,773,390 | C/T | — | uncertain significance |
| rs771134219 | 8:107,773,412 | A/C | — | uncertain significance |
| rs1483233284 | 8:107,773,452 | A/G | — | uncertain significance |
| rs753722518 | 8:107,773,474 | T/C | — | uncertain significance |
| rs756403095 | 8:107,773,488 | C/G | — | uncertain significance |
| rs182944429 | 8:107,773,510 | G/A | — | uncertain significance |
| rs747203470 | 8:107,773,587 | A/G | — | uncertain significance |
| rs201763716 | 8:107,773,636 | A/G | — | uncertain significance |
| rs766328261 | 8:107,781,766 | C/T | — | uncertain significance |
| rs551422006 | 8:107,781,767 | G/A | — | uncertain significance |
| rs2488203971 | 8:107,781,799 | T/C | — | uncertain significance |
| rs190365858 | 8:107,781,811 | C/T | — | uncertain significance |
| rs1266381212 | 8:107,781,836 | C/T | — | uncertain significance |
| rs770028905 | 8:107,781,855 | G/C | — | uncertain significance |
| rs113794783 | 8:107,781,872 | T/C | — | uncertain significance |
| rs1810572075 | 8:107,781,916 | G/C | — | uncertain significance |
| rs761154629 | 8:107,781,972 | T/G | — | uncertain significance |
| rs565264240 | 8:107,782,001 | G/A | — | uncertain significance |
| rs199815182 | 8:107,782,074 | G/T | — | uncertain significance |
| rs113926734 | 8:107,782,084 | G/A | — | uncertain significance |
| rs149735084 | 8:107,782,118 | C/A | — | uncertain significance |
| rs2488204758 | 8:107,782,162 | G/C | — | uncertain significance |
| rs753744299 | 8:107,782,211 | T/C | — | uncertain significance |
| rs769872145 | 8:107,782,219 | G/A | — | likely benign |
| rs747231998 | 8:107,782,234 | G/A | — | uncertain significance |
| rs757563640 | 8:107,782,235 | C/T | — | uncertain significance |
| rs781527207 | 8:107,782,249 | T/C | — | uncertain significance |
| rs747564086 | 8:107,782,258 | C/G | — | uncertain significance |
| rs2488205136 | 8:107,782,325 | C/G | — | uncertain significance |
| rs543076495 | 8:107,782,357 | C/T | — | uncertain significance |
| rs746468635 | 8:107,782,396 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.