ACKR4
atypical chemokine receptor 4
Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
Known Variants5 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs141386637 | 3:132,319,810 | G/A | missense variant | — |
| rs2530038350 | 3:132,320,044 | T/C | — | uncertain significance |
| rs368529492 | 3:132,320,082 | A/G | — | uncertain significance |
| rs546618608 | 3:132,320,083 | T/C | — | uncertain significance |
| rs758063654 | 3:132,320,130 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.