ACOD1
aconitate decarboxylase 1
Summary
Enables aconitate decarboxylase activity and protein homodimerization activity. Involved in defense response; positive regulation of antimicrobial humoral response; and tolerance induction to lipopolysaccharide. Predicted to be active in mitochondrion. Biomarker of esophageal carcinoma and head and neck squamous cell carcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants5 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs192457026 | 13:77,527,743 | T/G | — | likely benign |
| rs611161 | 13:77,527,791 | G/T | — | benign |
| rs140596263 | 13:77,529,451 | C/T | — | benign |
| rs640192 | 13:77,529,644 | A/G | — | benign |
| rs61741168 | 13:77,531,492 | G/A | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.