ACTL8
actin like 8
Summary
Predicted to enable protein kinase binding activity. Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Involved in epithelial cell differentiation. Predicted to be located in cytoskeleton. Predicted to be part of NuA4 histone acetyltransferase complex. Predicted to be active in several cellular components, including actin filament; axon; and synapse. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs773193212 | 1:18,149,519 | G/C | — | uncertain significance |
| rs750983259 | 1:18,149,559 | C/T | — | uncertain significance |
| rs747728884 | 1:18,149,564 | G/A | — | uncertain significance |
| rs1336491296 | 1:18,149,685 | A/G | — | uncertain significance |
| rs201038955 | 1:18,149,715 | G/T | — | uncertain significance |
| rs138844094 | 1:18,149,720 | C/G | — | uncertain significance |
| rs758261864 | 1:18,149,807 | G/A | — | uncertain significance |
| rs924872941 | 1:18,152,404 | G/A | — | uncertain significance |
| rs540944325 | 1:18,152,442 | G/A | — | uncertain significance |
| rs771963695 | 1:18,152,458 | C/T | — | uncertain significance |
| rs372611534 | 1:18,152,526 | G/A | — | uncertain significance |
| rs142430342 | 1:18,152,530 | T/G | — | uncertain significance |
| rs745438404 | 1:18,152,569 | G/C | — | uncertain significance |
| rs746694408 | 1:18,152,574 | G/A | — | uncertain significance |
| rs148049229 | 1:18,152,649 | G/A | — | uncertain significance |
| rs751796228 | 1:18,152,671 | G/A | — | uncertain significance |
| rs1384837832 | 1:18,152,703 | G/T | — | uncertain significance |
| rs755865643 | 1:18,152,734 | G/A | — | likely benign |
| rs761008927 | 1:18,152,772 | C/G | — | uncertain significance |
| rs2522323606 | 1:18,152,874 | T/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.