ACTR2

actin related protein 2

Summary

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Known Variants10 total

rsidPosition (GRCh37)AllelesClassClinVar
rs3755369732:65,469,190A/Guncertain significance
rs25285334822:65,473,706G/Auncertain significance
rs7795875902:65,478,188G/Auncertain significance
rs25285521782:65,482,728C/Tuncertain significance
rs5535246202:65,482,773T/Cuncertain significance
rs25285759342:65,492,281T/Guncertain significance
rs25285840882:65,495,706G/Tuncertain significance
rs25285840912:65,495,709C/Guncertain significance
rs101162:65,496,729G/A3 prime UTR variant
rs621390612:65,498,805T/Cdownstream gene variant

Gene information from NCBI Gene. Variant classifications from ClinVar.