ADCYAP1
adenylate cyclase activating polypeptide 1
Summary
This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Known Variants10 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1893154 | 18:905,125 | A/G | coding sequence variant | — |
| rs1381687555 | 18:905,457 | A/C | — | uncertain significance |
| rs765029234 | 18:905,473 | C/T | — | uncertain significance |
| rs2510033758 | 18:907,703 | G/A | — | uncertain significance |
| rs774534318 | 18:907,725 | C/G | — | uncertain significance |
| rs1395923101 | 18:907,767 | C/T | — | uncertain significance |
| rs144732014 | 18:908,300 | C/T | — | uncertain significance |
| rs753870869 | 18:908,303 | A/C | — | uncertain significance |
| rs778889031 | 18:908,307 | T/C | — | uncertain significance |
| rs372357255 | 18:908,343 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.