ADGRL2

adhesion G protein-coupled receptor L2

Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Known Variants106 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs142913971	1:81,831,677	T/C	—	—
rs11809789	1:82,074,852	G/A	intron variant	—
rs9729508	1:82,165,127	C/A	regulatory region variant	—
rs180843162	1:82,173,898	G/A	intron variant	—
rs11163372	1:82,247,248	C/T	intron variant	—
rs1286410138	1:82,302,661	G/A	—	likely benign
rs148990237	1:82,302,677	C/T	—	uncertain significance
rs138982442	1:82,302,695	G/A	—	likely benign
rs777246913	1:82,302,713	T/C	—	uncertain significance
rs570213848	1:82,364,795	T/C	—	—
rs2094597982	1:82,372,722	C/G	—	uncertain significance
rs550434713	1:82,372,751	C/T	—	likely benign
rs748207651	1:82,372,773	C/G	—	uncertain significance
rs142992362	1:82,372,803	A/G	—	uncertain significance
rs412378	1:82,374,494	G/A	intron variant	—
rs651533	1:82,375,561	T/A	intron variant	—
rs3790908	1:82,380,308	G/A	intron variant	—
rs3790904	1:82,382,517	G/T	intron variant	—
rs12032052	1:82,383,979	A/G	intron variant	—
rs17429851	1:82,390,031	A/C	intron variant	—
rs2182601	1:82,396,801	C/T	intron variant	—
rs6681544	1:82,398,544	C/A	—	—
rs747123560	1:82,402,412	G/T	—	uncertain significance
rs774334338	1:82,402,445	T/A	—	likely benign
rs774724301	1:82,408,814	G/T	—	uncertain significance
rs759705946	1:82,408,856	T/C	—	uncertain significance
rs2536140057	1:82,409,148	T/A	—	uncertain significance
rs149165038	1:82,409,269	C/T	—	likely benign
rs1389921950	1:82,409,348	A/G	—	uncertain significance
rs1648828998	1:82,409,400	A/G	—	uncertain significance
rs2536154264	1:82,409,420	T/C	—	uncertain significance
rs763820650	1:82,409,447	G/A	—	uncertain significance
rs75047930	1:82,413,823	C/A	—	—
rs539643450	1:82,415,911	C/G	—	uncertain significance
rs367932426	1:82,415,930	C/T	—	uncertain significance
rs370794666	1:82,415,950	C/G	—	uncertain significance
rs138125465	1:82,415,982	A/T	—	benign
rs1369210729	1:82,416,023	T/C	—	uncertain significance
rs1323036742	1:82,416,051	A/G	—	likely benign
rs759016504	1:82,416,716	C/T	—	uncertain significance
rs1394140104	1:82,416,722	A/G	—	uncertain significance
rs2536500989	1:82,416,749	A/G	—	uncertain significance
rs1307000905	1:82,416,771	G/A	—	uncertain significance
rs201068501	1:82,417,649	C/T	—	likely benign
rs141619218	1:82,417,696	A/G	—	likely benign
rs533343795	1:82,417,731	G/A	—	uncertain significance
rs141216171	1:82,417,766	T/C	—	benign
rs368142284	1:82,417,773	C/T	—	likely benign
rs372868281	1:82,421,617	A/G	—	likely benign
rs781134792	1:82,421,640	C/G	—	uncertain significance
rs199758386	1:82,421,742	T/C	—	uncertain significance
rs1327021	1:82,428,554	C/T	intron variant	—
rs142415541	1:82,431,756	G/T	—	uncertain significance
rs747889657	1:82,431,801	G/A	—	uncertain significance
rs759899407	1:82,431,837	G/A	—	uncertain significance
rs141656433	1:82,432,184	G/T	—	likely benign
rs151060845	1:82,432,221	A/G	—	likely benign
rs190474171	1:82,432,239	G/A	—	likely benign
rs150187776	1:82,432,242	C/T	—	benign
rs374306241	1:82,433,825	C/T	—	uncertain significance
rs369954151	1:82,434,932	G/C	—	uncertain significance
rs2537331804	1:82,434,979	A/G	—	uncertain significance
rs1558021601	1:82,435,010	G/C	—	uncertain significance
rs757239872	1:82,435,994	G/A	—	likely benign
rs368282486	1:82,436,037	T/A	—	uncertain significance
rs1257035314	1:82,436,130	T/A	—	uncertain significance
rs1386101630	1:82,436,181	G/A	—	uncertain significance
rs752414849	1:82,437,547	A/G	—	uncertain significance
rs372672882	1:82,437,577	T/C	—	uncertain significance
rs756610656	1:82,445,596	A/C	—	uncertain significance
rs1477866800	1:82,445,623	C/G	—	uncertain significance
rs2537916741	1:82,447,500	T/G	—	uncertain significance
rs764559323	1:82,447,647	C/T	—	uncertain significance
rs1262749329	1:82,450,318	C/T	—	uncertain significance
rs41292982	1:82,450,365	A/G	—	benign
rs748702474	1:82,450,376	G/A	—	uncertain significance
rs143415657	1:82,450,382	C/A	—	uncertain significance
rs868449264	1:82,450,997	T/G	—	uncertain significance
rs772523265	1:82,451,016	A/G	—	uncertain significance
rs188777224	1:82,452,681	A/G	—	benign
rs76995529	1:82,453,022	G/A	—	benign
rs183237089	1:82,453,556	C/A	—	likely benign
rs72719419	1:82,456,107	G/C	—	benign
rs151184559	1:82,456,145	C/T	—	likely benign
rs143448377	1:82,456,165	G/T	—	benign
rs138336807	1:82,456,182	G/A	—	uncertain significance
rs998545121	1:82,456,198	G/A	—	uncertain significance
rs144340670	1:82,456,209	C/A	—	uncertain significance
rs748402076	1:82,456,266	C/T	—	uncertain significance
rs61741047	1:82,456,301	G/A	—	benign
rs146536254	1:82,456,308	G/A	—	benign
rs755347765	1:82,456,314	C/T	—	uncertain significance
rs146227933	1:82,456,332	A/G	—	benign
rs772363344	1:82,456,375	T/C	—	uncertain significance
rs368144102	1:82,456,428	C/A	—	uncertain significance
rs148181687	1:82,456,432	T/C	—	likely benign
rs767448584	1:82,456,489	G/A	—	uncertain significance
rs74098542	1:82,456,501	A/G	—	benign
rs764749995	1:82,456,526	T/C	—	likely benign
rs1664472243	1:82,456,533	C/T	—	uncertain significance

Showing 100 of 106 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.