ADGRL4
adhesion G protein-coupled receptor L4
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. Biomarker of glioblastoma and hypertrophic cardiomyopathy. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants43 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs777620699 | 1:79,356,870 | T/C | — | uncertain significance |
| rs2523283314 | 1:79,357,219 | A/G | — | uncertain significance |
| rs2523283334 | 1:79,357,233 | T/A | — | uncertain significance |
| rs2523283406 | 1:79,357,277 | G/C | — | uncertain significance |
| rs2275902 | 1:79,357,360 | G/C | missense variant | — |
| rs747993330 | 1:79,358,801 | C/T | — | uncertain significance |
| rs201768435 | 1:79,358,811 | G/A | — | uncertain significance |
| rs369384378 | 1:79,358,817 | A/T | — | uncertain significance |
| rs375073432 | 1:79,383,331 | G/C | — | uncertain significance |
| rs533550002 | 1:79,383,370 | G/A | — | likely benign |
| rs1230376119 | 1:79,383,516 | C/T | — | uncertain significance |
| rs191635062 | 1:79,383,554 | G/A | — | uncertain significance |
| rs765307430 | 1:79,383,560 | C/T | — | uncertain significance |
| rs2523322725 | 1:79,383,564 | C/T | — | uncertain significance |
| rs1304608471 | 1:79,383,660 | T/C | — | uncertain significance |
| rs2523326651 | 1:79,385,900 | A/G | — | uncertain significance |
| rs189385131 | 1:79,385,958 | G/T | — | uncertain significance |
| rs2523327000 | 1:79,386,058 | T/C | — | uncertain significance |
| rs1422580251 | 1:79,387,392 | C/T | — | uncertain significance |
| rs767286930 | 1:79,392,730 | C/A | — | uncertain significance |
| rs561425488 | 1:79,392,740 | A/G | — | uncertain significance |
| rs1357607643 | 1:79,392,767 | G/A | — | uncertain significance |
| rs773556383 | 1:79,392,771 | C/A | — | uncertain significance |
| rs12030712 | 1:79,401,106 | G/A | — | — |
| rs1444563288 | 1:79,402,016 | T/C | — | uncertain significance |
| rs11802443 | 1:79,402,017 | A/G | — | benign |
| rs369699141 | 1:79,403,500 | G/A | — | uncertain significance |
| rs773726466 | 1:79,403,669 | C/A | — | uncertain significance |
| rs767573062 | 1:79,403,916 | T/C | — | uncertain significance |
| rs1444494787 | 1:79,404,878 | T/C | — | uncertain significance |
| rs371749654 | 1:79,404,908 | A/T | — | uncertain significance |
| rs774842079 | 1:79,404,924 | G/A | — | likely benign |
| rs2523374343 | 1:79,411,977 | C/T | — | uncertain significance |
| rs200973848 | 1:79,412,068 | A/T | — | uncertain significance |
| rs771201747 | 1:79,412,073 | C/T | — | uncertain significance |
| rs199976603 | 1:79,412,099 | C/T | — | uncertain significance |
| rs10493618 | 1:79,441,458 | C/G | — | — |
| rs78253602 | 1:79,442,490 | A/G | — | — |
| rs12128198 | 1:79,445,538 | C/T | intron variant | — |
| rs12073294 | 1:79,466,218 | A/C | — | — |
| rs10874004 | 1:79,466,892 | A/C | — | — |
| rs200894297 | 1:79,470,788 | C/T | — | uncertain significance |
| rs368762765 | 1:79,470,824 | T/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.