ADM2
adrenomedullin 2
Summary
This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs200343776 | 22:50,920,324 | C/G | missense variant | — |
| rs537506034 | 22:50,921,009 | C/T | — | uncertain significance |
| rs549854733 | 22:50,921,013 | G/C | — | likely benign |
| rs201693188 | 22:50,921,052 | G/A | — | uncertain significance |
| rs759547085 | 22:50,921,070 | T/C | — | uncertain significance |
| rs374822745 | 22:50,921,076 | G/A | — | likely benign |
| rs995165560 | 22:50,921,109 | C/T | — | uncertain significance |
| rs1376539243 | 22:50,921,115 | T/C | — | likely benign |
| rs200276239 | 22:50,921,132 | C/A | — | benign |
| rs760679453 | 22:50,921,145 | G/A | — | uncertain significance |
| rs753656827 | 22:50,921,154 | C/T | — | uncertain significance |
| rs200616941 | 22:50,921,198 | C/T | — | uncertain significance |
| rs770975376 | 22:50,921,204 | C/G | — | uncertain significance |
| rs370815600 | 22:50,921,223 | G/A | — | uncertain significance |
| rs765846835 | 22:50,921,247 | G/C | — | uncertain significance |
| rs546959903 | 22:50,921,279 | G/A | — | uncertain significance |
| rs536506636 | 22:50,921,283 | G/A | — | uncertain significance |
| rs555246517 | 22:50,921,320 | C/G | — | uncertain significance |
| rs62239482 | 22:50,922,166 | C/G | regulatory region variant | — |
| rs761745 | 22:50,923,217 | T/C | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.