AGBL3
AGBL carboxypeptidase 3
Summary
Enables metallocarboxypeptidase activity. Involved in protein side chain deglutamylation. Predicted to be located in cytosol. Predicted to be active in centriole and cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants56 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1029286778 | 7:134,674,050 | C/T | — | uncertain significance |
| rs148391971 | 7:134,678,250 | C/G | — | benign |
| rs2348049 | 7:134,678,253 | T/A | — | uncertain significance |
| rs750194969 | 7:134,678,258 | G/A | — | uncertain significance |
| rs186048202 | 7:134,678,273 | C/T | — | benign |
| rs117732894 | 7:134,678,327 | T/C | — | benign |
| rs777491552 | 7:134,678,339 | G/A | — | uncertain significance |
| rs541084151 | 7:134,678,382 | G/C | — | uncertain significance |
| rs1810601230 | 7:134,678,426 | A/T | — | uncertain significance |
| rs1815915465 | 7:134,717,622 | C/G | — | uncertain significance |
| rs756567736 | 7:134,717,628 | T/C | — | uncertain significance |
| rs773938960 | 7:134,717,646 | C/T | — | uncertain significance |
| rs377156405 | 7:134,717,648 | T/C | — | likely benign |
| rs926581325 | 7:134,718,910 | G/A | — | uncertain significance |
| rs548026172 | 7:134,718,928 | C/T | — | uncertain significance |
| rs74319573 | 7:134,718,954 | C/T | — | benign |
| rs1220943061 | 7:134,718,958 | C/A | — | uncertain significance |
| rs779574796 | 7:134,718,989 | G/A | — | likely benign |
| rs370944722 | 7:134,719,055 | G/T | — | uncertain significance |
| rs200274325 | 7:134,719,061 | G/A | — | uncertain significance |
| rs2536679185 | 7:134,719,102 | A/G | — | uncertain significance |
| rs971516257 | 7:134,719,117 | A/C | — | uncertain significance |
| rs1584901261 | 7:134,719,130 | T/G | — | uncertain significance |
| rs1423530860 | 7:134,719,229 | C/T | — | uncertain significance |
| rs556037195 | 7:134,719,297 | C/T | — | uncertain significance |
| rs747834688 | 7:134,719,343 | G/C | — | uncertain significance |
| rs975006265 | 7:134,719,402 | C/T | — | uncertain significance |
| rs370765062 | 7:134,719,403 | G/A | — | uncertain significance |
| rs1188304197 | 7:134,719,516 | C/T | — | uncertain significance |
| rs371418591 | 7:134,719,538 | T/C | — | uncertain significance |
| rs566335317 | 7:134,719,613 | G/C | — | uncertain significance |
| rs774834856 | 7:134,719,671 | G/A | — | uncertain significance |
| rs752418931 | 7:134,722,260 | G/A | — | uncertain significance |
| rs766482783 | 7:134,722,302 | C/A | — | uncertain significance |
| rs1311200916 | 7:134,728,836 | G/A | — | uncertain significance |
| rs117168663 | 7:134,730,252 | C/T | — | benign |
| rs1484217054 | 7:134,730,272 | G/A | — | uncertain significance |
| rs1033228476 | 7:134,730,602 | A/G | — | uncertain significance |
| rs1424019444 | 7:134,730,635 | T/C | — | uncertain significance |
| rs375014126 | 7:134,743,925 | G/A | — | uncertain significance |
| rs1172047284 | 7:134,743,949 | T/C | — | uncertain significance |
| rs781726631 | 7:134,761,162 | A/G | — | uncertain significance |
| rs190310134 | 7:134,764,969 | G/A | — | benign |
| rs1051945232 | 7:134,764,992 | A/T | — | uncertain significance |
| rs10215144 | 7:134,765,148 | G/A | intron variant | — |
| rs1294415538 | 7:134,800,206 | A/G | — | uncertain significance |
| rs757729721 | 7:134,800,213 | A/C | — | uncertain significance |
| rs116331035 | 7:134,819,584 | C/A | — | benign |
| rs148526262 | 7:134,819,601 | C/T | — | likely benign |
| rs1486519695 | 7:134,819,646 | C/T | — | uncertain significance |
| rs1471579496 | 7:134,819,670 | T/A | — | uncertain significance |
| rs892280382 | 7:134,819,685 | T/G | — | uncertain significance |
| rs1416978163 | 7:134,819,717 | C/T | — | likely benign |
| rs778046559 | 7:134,819,850 | G/C | — | uncertain significance |
| rs575836826 | 7:134,819,942 | A/C | — | uncertain significance |
| rs199898448 | 7:134,819,951 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.