AKAP11

A-kinase anchoring protein 11

Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]

Known Variants112 total

rsidPosition (GRCh37)AllelesClassClinVar
rs7873858113:42,843,630G/Aupstream gene variant—
rs53015765313:42,860,497A/G—uncertain significance
rs14450625313:42,866,585G/T—uncertain significance
rs11434566013:42,871,281A/G—benign
rs74638328613:42,871,298A/G—uncertain significance
rs75926391213:42,872,723C/G—uncertain significance
rs14024348713:42,872,814T/C—uncertain significance
rs254229881513:42,872,898T/C—uncertain significance
rs13798433313:42,872,906G/C—uncertain significance
rs130058150313:42,872,928A/T—uncertain significance
rs75562391313:42,873,549G/T—uncertain significance
rs76335158513:42,873,655A/G—uncertain significance
rs20065527713:42,873,708T/C—uncertain significance
rs37331191813:42,873,718G/T—uncertain significance
rs254230923913:42,873,820G/A—uncertain significance
rs77519260113:42,873,988T/C—uncertain significance
rs76295682613:42,873,997G/T—uncertain significance
rs97607121313:42,874,068A/G—uncertain significance
rs254231268213:42,874,075C/T—uncertain significance
rs77510474113:42,874,095C/T—uncertain significance
rs159433167513:42,874,101G/T—uncertain significance
rs142604674413:42,874,149C/G—uncertain significance
rs195976390313:42,874,156G/T—uncertain significance
rs254231427613:42,874,182C/T—uncertain significance
rs37637026013:42,874,285G/A—uncertain significance
rs254231611313:42,874,328T/G—uncertain significance
rs254231661213:42,874,363G/A—likely benign
rs254231671113:42,874,372G/A—uncertain significance
rs141588093513:42,874,411A/G—uncertain significance
rs75227694613:42,874,467A/C—uncertain significance
rs95296114613:42,874,506A/G—uncertain significance
rs254231931113:42,874,609G/A—uncertain significance
rs14739345113:42,874,615A/G—uncertain significance
rs77689757513:42,874,689C/T—likely benign
rs7540849113:42,874,690G/A—benign
rs6174884313:42,874,710C/T—benign
rs78109104813:42,874,803A/C—uncertain significance
rs75501420513:42,874,881T/C—uncertain significance
rs37518607213:42,874,884C/T—uncertain significance
rs54802069813:42,875,038G/A—uncertain significance
rs11805663813:42,875,047C/T—uncertain significance
rs195984904613:42,875,068G/A—uncertain significance
rs254232506413:42,875,103A/G—uncertain significance
rs19969699413:42,875,170A/G—uncertain significance
rs56919910813:42,875,214A/G—uncertain significance
rs75888825213:42,875,242G/T—uncertain significance
rs37677457513:42,875,271A/G—uncertain significance
rs37656378613:42,875,359G/C—uncertain significance
rs129215619013:42,875,368A/C—uncertain significance
rs119510856713:42,875,376T/A—uncertain significance
rs195988683413:42,875,456A/C—uncertain significance
rs77824411213:42,875,530T/A—uncertain significance
rs37476874213:42,875,545T/C—uncertain significance
rs6175250013:42,875,587A/G—benign
rs56164502913:42,875,589C/T—uncertain significance
rs6175253613:42,875,590G/A—likely benign
rs77225206113:42,875,670G/A—uncertain significance
rs19985044813:42,875,703C/T—uncertain significance
rs75110343213:42,875,718A/G—uncertain significance
rs128868154013:42,875,734T/C—uncertain significance
rs74709636513:42,875,776C/T—likely benign
rs37063647213:42,875,802T/G—uncertain significance
rs1706316313:42,876,091A/G—benign
rs6175656613:42,876,103C/T—benign
rs74847152113:42,876,189T/A—uncertain significance
rs15132968313:42,876,205C/T—uncertain significance
rs14126728413:42,876,324A/G—uncertain significance
rs78080044213:42,876,376A/G—uncertain significance
rs76970750013:42,876,381A/T—uncertain significance
rs20124170213:42,876,464G/T—uncertain significance
rs36934077313:42,876,514C/G—uncertain significance
rs37387627013:42,876,666G/T—uncertain significance
rs78030879513:42,876,723A/G—likely benign
rs141363711313:42,876,733A/T—uncertain significance
rs14134489513:42,876,743G/C—uncertain significance
rs78088867913:42,876,798A/G—likely benign
rs6175597513:42,876,833G/A—likely benign
rs6175754713:42,876,835T/G—likely benign
rs54609956313:42,876,880A/G—uncertain significance
rs254234879213:42,876,889C/T—uncertain significance
rs254234972113:42,876,972A/G—uncertain significance
rs141354229013:42,877,057A/G—likely benign
rs74888983613:42,877,067G/A—uncertain significance
rs14736054713:42,877,072C/T—uncertain significance
rs254235165713:42,877,125A/G—uncertain significance
rs7510669013:42,877,257A/G—benign
rs75442172913:42,877,306C/T—uncertain significance
rs53433492713:42,877,314G/A—uncertain significance
rs125699155813:42,877,407A/C—uncertain significance
rs37304322313:42,877,417A/G—uncertain significance
rs75989871313:42,877,486A/G—uncertain significance
rs96017125113:42,877,520A/T—uncertain significance
rs36941072613:42,877,548C/G—uncertain significance
rs105297644113:42,877,595C/A—uncertain significance
rs37231807013:42,877,719G/C—uncertain significance
rs6175363013:42,877,758C/T—benign
rs14960815713:42,877,799G/T—uncertain significance
rs36841387813:42,877,804A/T—uncertain significance
rs139340237413:42,877,833G/T—uncertain significance
rs75904689013:42,877,834C/G—uncertain significance

Showing 100 of 112 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.