ALDH3B2
aldehyde dehydrogenase 3 family member B2
Summary
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. Altered methylation patterns at this locus have been observed in spermatozoa derived from patients exhibiting reduced fecundity. [provided by RefSeq, Aug 2017]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1368259335 | 11:67,430,696 | G/A | — | uncertain significance |
| rs140105486 | 11:67,430,723 | C/T | — | uncertain significance |
| rs757916431 | 11:67,430,745 | C/T | — | uncertain significance |
| rs767104617 | 11:67,430,787 | C/T | — | uncertain significance |
| rs180859869 | 11:67,431,199 | C/T | — | uncertain significance |
| rs147016371 | 11:67,431,887 | C/T | — | uncertain significance |
| rs2495854628 | 11:67,431,899 | G/C | — | uncertain significance |
| rs560092704 | 11:67,431,910 | T/C | — | likely benign |
| rs771376111 | 11:67,431,932 | C/T | — | uncertain significance |
| rs1189090762 | 11:67,431,940 | A/G | — | uncertain significance |
| rs762624725 | 11:67,431,941 | C/T | — | uncertain significance |
| rs199918120 | 11:67,432,006 | T/C | — | uncertain significance |
| rs566460680 | 11:67,432,031 | G/A | — | uncertain significance |
| rs761186674 | 11:67,432,768 | C/T | — | uncertain significance |
| rs142842552 | 11:67,432,774 | C/T | — | uncertain significance |
| rs1239062786 | 11:67,432,852 | T/A | — | uncertain significance |
| rs746299588 | 11:67,432,894 | A/T | — | uncertain significance |
| rs140215620 | 11:67,432,957 | C/T | — | likely benign |
| rs754993637 | 11:67,432,961 | G/C | — | uncertain significance |
| rs1224877653 | 11:67,432,962 | T/G | — | uncertain significance |
| rs777929652 | 11:67,432,972 | C/T | — | uncertain significance |
| rs1289683802 | 11:67,433,008 | C/T | — | uncertain significance |
| rs150455483 | 11:67,433,013 | C/T | — | uncertain significance |
| rs140738572 | 11:67,433,050 | C/T | — | uncertain significance |
| rs1184625784 | 11:67,433,619 | T/A | — | uncertain significance |
| rs139967003 | 11:67,433,650 | C/T | — | uncertain significance |
| rs1244674691 | 11:67,433,672 | G/C | — | uncertain significance |
| rs1442714705 | 11:67,433,831 | T/C | — | uncertain significance |
| rs752296344 | 11:67,433,864 | C/T | — | uncertain significance |
| rs1871032 | 11:67,434,010 | C/T | intron variant | — |
| rs1140671 | 11:67,434,051 | C/T | — | uncertain significance |
| rs1140670 | 11:67,434,057 | C/T | — | uncertain significance |
| rs1221342685 | 11:67,434,097 | C/G | — | uncertain significance |
| rs766393325 | 11:67,434,129 | G/T | — | uncertain significance |
| rs189634559 | 11:67,434,391 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.