ALDOC
aldolase, fructose-bisphosphate C
Summary
This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]
Known Variants22 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs371687048 | 17:26,900,800 | G/T | — | likely benign |
| rs1441393520 | 17:26,900,841 | C/T | — | uncertain significance |
| rs150324059 | 17:26,900,862 | G/A | — | uncertain significance |
| rs765845189 | 17:26,901,108 | C/T | — | uncertain significance |
| rs2508505489 | 17:26,901,158 | G/C | — | uncertain significance |
| rs138221835 | 17:26,901,177 | G/A | — | uncertain significance |
| rs117717144 | 17:26,901,523 | C/T | — | uncertain significance |
| rs182794210 | 17:26,901,534 | C/T | — | uncertain significance |
| rs569950345 | 17:26,901,537 | T/C | — | uncertain significance |
| rs747367976 | 17:26,901,737 | G/A | — | uncertain significance |
| rs201385668 | 17:26,901,748 | T/C | — | uncertain significance |
| rs2070466746 | 17:26,901,778 | G/A | — | uncertain significance |
| rs142754133 | 17:26,901,785 | G/A | — | uncertain significance |
| rs1288722081 | 17:26,901,809 | G/A | — | uncertain significance |
| rs371220607 | 17:26,901,847 | G/T | — | uncertain significance |
| rs34703826 | 17:26,902,006 | G/C | — | uncertain significance |
| rs761240800 | 17:26,902,178 | C/T | — | uncertain significance |
| rs201657122 | 17:26,902,236 | C/T | — | uncertain significance |
| rs752045255 | 17:26,902,474 | G/A | — | uncertain significance |
| rs778618371 | 17:26,902,496 | T/C | — | uncertain significance |
| rs2508510084 | 17:26,902,544 | G/T | — | uncertain significance |
| rs141921160 | 17:26,903,928 | C/T | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.