ALKAL1
ALK and LTK ligand 1
Summary
Enables protein tyrosine kinase activator activity and signaling receptor binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of MAPK cascade; and positive regulation of neuron projection development. Is active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants9 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs145116532 | 8:53,452,429 | C/A | — | uncertain significance |
| rs2486811771 | 8:53,452,453 | G/T | — | uncertain significance |
| rs1377359787 | 8:53,477,638 | G/A | — | uncertain significance |
| rs933499185 | 8:53,477,647 | G/C | — | uncertain significance |
| rs1271411549 | 8:53,477,665 | G/A | — | uncertain significance |
| rs573676247 | 8:53,477,681 | G/C | — | uncertain significance |
| rs577185547 | 8:53,477,767 | G/A | — | uncertain significance |
| rs763736740 | 8:53,477,780 | G/C | — | uncertain significance |
| rs2486852230 | 8:53,477,786 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.