AMY2B
amylase alpha 2B
Summary
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
Known Variants51 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs150391908 | 1:104,102,557 | C/G | downstream gene variant | — |
| rs752281162 | 1:104,114,231 | T/C | — | uncertain significance |
| rs757208411 | 1:104,114,238 | T/G | — | uncertain significance |
| rs140146360 | 1:104,114,252 | A/T | — | uncertain significance |
| rs139632093 | 1:104,114,298 | G/A | — | uncertain significance |
| rs746296699 | 1:104,114,310 | T/C | — | uncertain significance |
| rs12128421 | 1:104,114,315 | C/A | — | uncertain significance |
| rs558718174 | 1:104,114,358 | G/C | — | uncertain significance |
| rs141409903 | 1:104,114,369 | C/A | — | uncertain significance |
| rs774157974 | 1:104,114,376 | G/A | — | uncertain significance |
| rs201971305 | 1:104,114,756 | G/A | — | uncertain significance |
| rs762791161 | 1:104,114,759 | A/G | — | likely benign |
| rs2524214766 | 1:104,114,829 | G/C | — | uncertain significance |
| rs780789568 | 1:104,114,838 | A/G | — | uncertain significance |
| rs4098273 | 1:104,115,722 | C/G | — | likely benign |
| rs1413069303 | 1:104,115,848 | G/C | — | uncertain significance |
| rs142284584 | 1:104,116,375 | A/C | — | uncertain significance |
| rs1652233618 | 1:104,116,403 | A/T | — | uncertain significance |
| rs200461293 | 1:104,116,427 | T/A | — | uncertain significance |
| rs2524221752 | 1:104,116,430 | G/C | — | uncertain significance |
| rs2524221835 | 1:104,116,462 | C/A | — | uncertain significance |
| rs2524221842 | 1:104,116,465 | A/T | — | uncertain significance |
| rs137860562 | 1:104,116,544 | C/A | — | uncertain significance |
| rs753090470 | 1:104,116,897 | G/C | — | uncertain significance |
| rs12131520 | 1:104,116,920 | C/T | — | likely benign |
| rs200275225 | 1:104,116,937 | G/A | — | uncertain significance |
| rs368462934 | 1:104,116,981 | C/T | — | uncertain significance |
| rs201396892 | 1:104,116,982 | G/A | — | uncertain significance |
| rs184979235 | 1:104,116,993 | G/A | — | uncertain significance |
| rs1256726781 | 1:104,117,012 | T/G | — | uncertain significance |
| rs2524229723 | 1:104,117,961 | A/T | — | uncertain significance |
| rs145913863 | 1:104,118,077 | C/T | — | uncertain significance |
| rs150608402 | 1:104,118,134 | G/A | — | uncertain significance |
| rs1201672301 | 1:104,118,137 | G/T | — | uncertain significance |
| rs757818865 | 1:104,118,138 | G/T | — | uncertain significance |
| rs1171955418 | 1:104,118,143 | G/C | — | uncertain significance |
| rs767668528 | 1:104,120,127 | G/A | — | likely benign |
| rs754296775 | 1:104,120,142 | A/T | — | uncertain significance |
| rs1417938391 | 1:104,120,181 | A/G | — | uncertain significance |
| rs768084085 | 1:104,120,215 | G/A | — | uncertain significance |
| rs767168411 | 1:104,120,358 | C/T | — | uncertain significance |
| rs749967894 | 1:104,120,359 | G/A | — | uncertain significance |
| rs2101080083 | 1:104,120,418 | G/A | — | uncertain significance |
| rs192985193 | 1:104,121,447 | T/A | intron variant | — |
| rs544997650 | 1:104,121,940 | T/A | — | uncertain significance |
| rs2524248807 | 1:104,121,949 | T/G | — | uncertain significance |
| rs758807572 | 1:104,121,971 | G/C | — | uncertain significance |
| rs147068794 | 1:104,122,010 | G/A | — | uncertain significance |
| rs143243690 | 1:104,122,036 | G/A | — | uncertain significance |
| rs139342062 | 1:104,122,057 | C/T | — | likely benign |
| rs778128001 | 1:104,122,066 | A/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.