ANAPC11
anaphase promoting complex subunit 11
Summary
Enables cullin family protein binding activity and ubiquitin-ubiquitin ligase activity. Contributes to ubiquitin-protein transferase activity. Involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein polyubiquitination. Located in nucleolus and nucleoplasm. Part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants4 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142854740 | 17:79,857,139 | T/C | — | uncertain significance |
| rs376590482 | 17:79,857,180 | C/G | — | uncertain significance |
| rs149063288 | 17:79,857,839 | C/T | — | uncertain significance |
| rs924392175 | 17:79,857,882 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.