ANAPC13
anaphase promoting complex subunit 13
Summary
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]
Known Variants3 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs772450733 | 3:134,197,454 | T/A | — | uncertain significance |
| rs1227102071 | 3:134,201,676 | A/C | — | uncertain significance |
| rs2546044977 | 3:134,201,677 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.