ANGEL2
angel homolog 2
Summary
Enables mRNA 3'-UTR binding activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of mitotic cell cycle. Located in Cajal body and cytoplasm. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants27 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs889685925 | 1:213,168,453 | T/C | — | uncertain significance |
| rs1325242772 | 1:213,168,457 | C/T | — | uncertain significance |
| rs567418545 | 1:213,168,517 | C/T | — | uncertain significance |
| rs972543902 | 1:213,168,526 | C/G | — | uncertain significance |
| rs982573649 | 1:213,170,562 | C/T | — | uncertain significance |
| rs2464816749 | 1:213,170,601 | G/A | — | uncertain significance |
| rs1305025409 | 1:213,174,253 | A/T | — | uncertain significance |
| rs41277166 | 1:213,178,383 | T/C | — | uncertain significance |
| rs149002480 | 1:213,178,499 | T/A | — | uncertain significance |
| rs2076288688 | 1:213,178,530 | T/C | — | uncertain significance |
| rs143448361 | 1:213,178,583 | G/A | — | uncertain significance |
| rs778100901 | 1:213,178,605 | G/A | — | uncertain significance |
| rs201180365 | 1:213,178,685 | C/A | — | uncertain significance |
| rs750306674 | 1:213,178,686 | G/A | — | uncertain significance |
| rs749390709 | 1:213,178,746 | C/T | — | uncertain significance |
| rs144576191 | 1:213,178,764 | T/C | — | uncertain significance |
| rs140064007 | 1:213,181,619 | C/T | — | uncertain significance |
| rs151245232 | 1:213,181,622 | C/T | — | uncertain significance |
| rs377486143 | 1:213,181,641 | G/A | — | uncertain significance |
| rs915459134 | 1:213,181,728 | G/C | — | uncertain significance |
| rs1034297844 | 1:213,181,772 | T/C | — | uncertain significance |
| rs150486074 | 1:213,181,806 | C/T | — | uncertain significance |
| rs770546728 | 1:213,186,462 | G/A | — | uncertain significance |
| rs2464965642 | 1:213,186,645 | C/T | — | uncertain significance |
| rs751427581 | 1:213,186,671 | T/C | — | uncertain significance |
| rs1333777506 | 1:213,186,731 | C/T | — | uncertain significance |
| rs2076626289 | 1:213,189,006 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.