ANKHD1-EIF4EBP3

ANKHD1-EIF4EBP3 readthrough

Summary

The ANKHD1-EIF4EBP3 mRNA is an infrequent but naturally occurring readthrough transcript of the neighboring ANKHD1 and EIF4EBP3 genes. This readthrough transcript encodes a protein composed mostly of the multiple ankyrin repeats, single KH-domain protein, with its C-terminus encoded in a different reading frame from the shared portion of the EIF4EBP3 gene. The significance of this readthrough mRNA and the function of its protein product have not yet been determined. [provided by RefSeq, Nov 2009]

Known Variants13 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1447291155:139,818,103G/Auncertain significance
rs3721200115:139,838,858T/Clikely benign
rs24807816445:139,905,751C/Tuncertain significance
rs7513198665:139,909,322A/Guncertain significance
rs2020174665:139,921,770C/Tuncertain significance
rs7533085275:139,921,805C/Guncertain significance
rs7797622235:139,921,823A/Guncertain significance
rs2015080645:139,921,838C/Tuncertain significance
rs7578139315:139,928,492C/Auncertain significance
rs7808224445:139,928,511C/Tuncertain significance
rs3756546165:139,928,513A/Cuncertain significance
rs10519321375:139,928,582C/Tuncertain significance
rs17544638325:139,928,642G/Auncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.