ANP32D
acidic nuclear phosphoprotein 32 family member D
Summary
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2499080457 | 12:48,866,487 | A/G | — | uncertain significance |
| rs750180206 | 12:48,866,491 | C/A | — | uncertain significance |
| rs777687157 | 12:48,866,499 | G/A | — | uncertain significance |
| rs2499080495 | 12:48,866,506 | A/G | — | uncertain significance |
| rs138630151 | 12:48,866,541 | G/T | — | uncertain significance |
| rs199783781 | 12:48,866,547 | T/A | — | uncertain significance |
| rs1954090967 | 12:48,866,652 | C/A | — | uncertain significance |
| rs1444978797 | 12:48,866,754 | C/T | — | uncertain significance |
| rs1350358650 | 12:48,866,808 | T/A | — | uncertain significance |
| rs113589703 | 12:48,866,827 | A/T | — | uncertain significance |
| rs1404341802 | 12:48,866,833 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.