AOX1

aldehyde oxidase 1

Summary

Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]

Known Variants62 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs769152037	2:201,450,841	G/C	—	uncertain significance
rs372717699	2:201,457,869	G/A	—	uncertain significance
rs1225253123	2:201,460,004	C/T	—	uncertain significance
rs2470100257	2:201,462,146	T/C	—	likely benign
rs2470100283	2:201,462,151	A/G	—	uncertain significance
rs759214228	2:201,464,383	G/A	—	uncertain significance
rs1323020890	2:201,464,410	A/G	—	uncertain significance
rs142144384	2:201,464,423	G/A	—	benign
rs1338790587	2:201,468,037	T/A	—	uncertain significance
rs770784669	2:201,468,747	C/T	—	uncertain significance
rs529389023	2:201,468,785	C/G	—	uncertain significance
rs756216774	2:201,469,466	G/A	—	likely benign
rs2470119255	2:201,469,513	T/G	—	uncertain significance
rs781753651	2:201,470,274	T/A	—	uncertain significance
rs73049078	2:201,470,354	G/A	—	benign
rs765302652	2:201,473,719	G/A	—	uncertain significance
rs58185012	2:201,473,740	A/G	—	benign
rs2470129595	2:201,474,078	A/T	—	uncertain significance
rs147455669	2:201,476,116	G/A	—	uncertain significance
rs1179169587	2:201,476,119	A/T	—	uncertain significance
rs1477876544	2:201,477,371	G/T	—	uncertain significance
rs896852817	2:201,477,374	A/G	—	uncertain significance
rs141842645	2:201,478,527	G/A	—	likely benign
rs1475976051	2:201,478,561	A/G	—	uncertain significance
rs201421164	2:201,478,585	C/G	—	uncertain significance
rs1230063917	2:201,478,600	C/T	—	uncertain significance
rs1178743003	2:201,478,663	G/C	—	uncertain significance
rs114483614	2:201,480,739	T/C	—	benign
rs2034866136	2:201,485,376	A/G	—	likely benign
rs373513974	2:201,485,424	C/A	—	uncertain significance
rs143935618	2:201,485,461	T/A	—	benign
rs1385782137	2:201,485,929	G/A	—	uncertain significance
rs562776296	2:201,488,592	T/C	—	likely benign
rs200732153	2:201,488,602	C/T	—	uncertain significance
rs2470164832	2:201,488,626	T/G	—	uncertain significance
rs150316811	2:201,488,688	G/A	—	likely benign
rs16833923	2:201,492,162	A/G	—	benign
rs372341427	2:201,499,573	G/A	—	uncertain significance
rs1264892938	2:201,499,601	A/G	—	uncertain significance
rs145900999	2:201,501,635	A/T	—	uncertain significance
rs149839944	2:201,501,687	A/G	—	likely benign
rs774045453	2:201,501,689	G/A	—	likely benign
rs201083953	2:201,501,764	A/G	—	uncertain significance
rs1041305387	2:201,505,873	G/A	—	uncertain significance
rs2470209611	2:201,507,343	T/C	—	uncertain significance
rs1331295104	2:201,507,435	T/C	—	likely benign
rs188829065	2:201,513,173	G/A	intron variant	—
rs1206077534	2:201,515,769	A/G	—	uncertain significance
rs1262952201	2:201,515,770	T/C	—	uncertain significance
rs774101325	2:201,515,910	C/T	—	uncertain significance
rs201377782	2:201,521,561	T/G	—	likely benign
rs2035697233	2:201,521,577	G/C	—	uncertain significance
rs114924183	2:201,521,609	C/T	—	likely benign
rs139092129	2:201,523,964	C/G	—	benign
rs2035790586	2:201,524,754	A/C	—	uncertain significance
rs55754655	2:201,526,330	A/G	missense variant	—
rs774851026	2:201,527,588	T/G	—	uncertain significance
rs142723794	2:201,527,627	G/A	—	uncertain significance
rs1275710774	2:201,531,465	A/G	—	uncertain significance
rs73055188	2:201,532,698	G/A	intron variant	—
rs145877467	2:201,533,463	C/T	—	benign
rs78467837	2:201,533,520	A/G	—	benign

Gene information from NCBI Gene. Variant classifications from ClinVar.