APOBEC3F
apolipoprotein B mRNA editing enzyme catalytic subunit 3F
Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1231683015 | 22:39,436,972 | C/A | — | uncertain significance |
| rs147139507 | 22:39,439,009 | C/G | — | uncertain significance |
| rs773777133 | 22:39,440,970 | G/C | — | uncertain significance |
| rs556837667 | 22:39,441,054 | A/G | — | uncertain significance |
| rs775088222 | 22:39,441,072 | G/A | — | uncertain significance |
| rs148886390 | 22:39,441,157 | G/A | — | uncertain significance |
| rs201454313 | 22:39,441,218 | C/A | — | uncertain significance |
| rs147329876 | 22:39,441,434 | A/C | — | likely benign |
| rs527685670 | 22:39,441,506 | C/A | — | uncertain significance |
| rs371538178 | 22:39,441,526 | G/A | — | uncertain significance |
| rs33913356 | 22:39,445,436 | G/A | — | benign |
| rs1247334506 | 22:39,445,485 | C/T | — | uncertain significance |
| rs1476504244 | 22:39,445,551 | C/G | — | uncertain significance |
| rs1372581607 | 22:39,445,558 | C/G | — | uncertain significance |
| rs377406880 | 22:39,445,560 | T/C | — | uncertain significance |
| rs143572747 | 22:39,448,142 | C/T | — | likely benign |
| rs565931497 | 22:39,448,146 | C/G | — | uncertain significance |
| rs151229697 | 22:39,448,238 | A/G | — | uncertain significance |
| rs12157816 | 22:39,448,275 | A/G | — | benign |
| rs142120855 | 22:39,448,310 | C/T | — | uncertain significance |
| rs1433950959 | 22:39,448,350 | G/C | — | uncertain significance |
| rs13056825 | 22:39,448,615 | A/G | — | likely benign |
| rs1239402493 | 22:39,448,623 | G/A | — | uncertain significance |
| rs146924719 | 22:39,448,695 | G/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.