APOD
apolipoprotein D
Summary
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs150401209 | 3:195,295,782 | T/C | — | likely benign |
| rs150664052 | 3:195,295,958 | T/C | — | likely benign |
| rs201787147 | 3:195,295,971 | C/T | — | uncertain significance |
| rs752071105 | 3:195,295,991 | G/A | — | uncertain significance |
| rs146246326 | 3:195,298,178 | G/C | — | uncertain significance |
| rs376458064 | 3:195,298,208 | C/G | — | uncertain significance |
| rs76929107 | 3:195,300,740 | C/T | — | benign |
| rs141030350 | 3:195,300,788 | G/A | — | uncertain significance |
| rs144811342 | 3:195,300,800 | A/C | — | benign |
| rs1577603895 | 3:195,300,801 | G/T | — | likely benign |
| rs375250089 | 3:195,300,806 | T/G | — | uncertain significance |
| rs751722415 | 3:195,300,824 | C/T | — | uncertain significance |
| rs183224694 | 3:195,306,248 | G/A | — | uncertain significance |
| rs559280753 | 3:195,306,259 | A/G | — | uncertain significance |
| rs5952 | 3:195,306,289 | A/G | — | benign |
| rs1720298363 | 3:195,306,302 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.