ARFGEF3

ARFGEF family member 3

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Predicted to be located in transport vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants163 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs74590195	6:138,491,854	G/A	—	benign
rs1777638109	6:138,528,231	C/G	—	uncertain significance
rs140881091	6:138,528,235	C/G	—	uncertain significance
rs141094520	6:138,531,092	G/T	—	likely benign
rs145271719	6:138,531,148	C/T	—	benign
rs115941727	6:138,531,151	C/A	—	uncertain significance
rs6927706	6:138,539,315	A/G	missense variant	—
rs373625094	6:138,559,653	T/C	—	uncertain significance
rs2482471875	6:138,564,090	T/A	—	uncertain significance
rs75188756	6:138,566,719	C/T	—	benign
rs149810556	6:138,566,720	C/T	—	likely benign
rs767321273	6:138,575,036	C/T	—	uncertain significance
rs144995312	6:138,575,088	T/C	—	uncertain significance
rs2482492146	6:138,575,092	C/A	—	uncertain significance
rs1457229732	6:138,575,099	A/T	—	uncertain significance
rs747548846	6:138,575,103	G/A	—	uncertain significance
rs2482495547	6:138,576,659	G/A	—	uncertain significance
rs144437178	6:138,576,750	A/G	—	likely benign
rs750706308	6:138,576,761	G/A	—	uncertain significance
rs1428850805	6:138,576,802	G/A	—	uncertain significance
rs1778662993	6:138,576,803	G/T	—	uncertain significance
rs141449825	6:138,576,826	G/A	—	uncertain significance
rs147994372	6:138,576,868	C/T	—	uncertain significance
rs951236569	6:138,576,878	G/A	—	uncertain significance
rs538057829	6:138,582,674	G/T	—	uncertain significance
rs368160702	6:138,582,683	G/A	—	uncertain significance
rs2482508189	6:138,582,731	A/G	—	uncertain significance
rs771657236	6:138,582,739	A/G	—	uncertain significance
rs138879312	6:138,583,856	C/T	—	benign
rs149573553	6:138,583,857	G/A	—	uncertain significance
rs34628698	6:138,583,868	C/T	—	benign
rs775704478	6:138,583,869	A/C	—	uncertain significance
rs144891965	6:138,583,967	T/G	—	benign
rs148727789	6:138,583,989	C/T	—	uncertain significance
rs116596107	6:138,584,014	C/G	—	conflicting classifications of pathogenicity
rs570967067	6:138,584,026	G/A	—	uncertain significance
rs34767816	6:138,584,092	C/T	—	benign
rs542995422	6:138,584,196	G/A	—	uncertain significance
rs9494985	6:138,584,264	G/A	—	benign
rs2482512540	6:138,584,289	G/A	—	uncertain significance
rs753750788	6:138,584,323	C/T	—	uncertain significance
rs1463360191	6:138,584,328	C/G	—	likely benign
rs374263641	6:138,584,466	A/G	—	uncertain significance
rs151159641	6:138,584,516	G/A	—	likely benign
rs758460913	6:138,584,550	C/T	—	uncertain significance
rs1778829412	6:138,584,580	C/T	—	uncertain significance
rs145746277	6:138,584,623	C/T	—	uncertain significance
rs1178223810	6:138,584,651	A/G	—	uncertain significance
rs7764091	6:138,584,685	T/G	—	benign
rs145180404	6:138,584,691	T/C	—	likely benign
rs138956668	6:138,584,706	G/T	—	uncertain significance
rs373292748	6:138,584,714	C/T	—	likely benign
rs556643571	6:138,584,715	G/A	—	uncertain significance
rs752657686	6:138,584,730	G/T	—	uncertain significance
rs61741354	6:138,584,731	C/T	—	benign
rs1779137602	6:138,599,599	T/C	—	uncertain significance
rs150705933	6:138,599,729	G/A	—	uncertain significance
rs371940953	6:138,599,749	G/T	—	uncertain significance
rs376150531	6:138,601,152	A/G	—	uncertain significance
rs148522096	6:138,601,166	G/A	—	uncertain significance
rs756244120	6:138,601,185	C/G	—	uncertain significance
rs760367751	6:138,601,239	G/C	—	uncertain significance
rs757313301	6:138,607,098	A/G	—	uncertain significance
rs761979008	6:138,607,175	G/C	—	uncertain significance
rs759459619	6:138,607,852	C/T	—	uncertain significance
rs1234578030	6:138,607,856	A/G	—	uncertain significance
rs201869171	6:138,607,922	C/T	—	uncertain significance
rs2482562300	6:138,607,968	C/G	—	uncertain significance
rs781511050	6:138,608,014	G/A	—	uncertain significance
rs367548672	6:138,608,058	C/A	—	likely benign
rs200030187	6:138,608,205	C/G	—	likely benign
rs17568867	6:138,608,212	T/C	—	benign
rs773124641	6:138,611,026	G/A	—	uncertain significance
rs777578890	6:138,611,097	C/T	—	likely benign
rs117533399	6:138,612,882	C/T	—	likely benign
rs940512268	6:138,612,883	G/T	—	uncertain significance
rs372133127	6:138,612,977	T/C	—	uncertain significance
rs764225934	6:138,613,033	C/T	—	uncertain significance
rs772843349	6:138,613,063	C/T	—	uncertain significance
rs748859564	6:138,613,066	C/A	—	uncertain significance
rs751218609	6:138,613,075	C/G	—	uncertain significance
rs1030633854	6:138,613,087	C/T	—	uncertain significance
rs369929834	6:138,613,140	C/T	—	likely benign
rs371919461	6:138,613,141	G/A	—	uncertain significance
rs776940549	6:138,613,142	G/A	—	uncertain significance
rs576282820	6:138,613,143	G/A	—	likely benign
rs762943127	6:138,613,151	C/T	—	uncertain significance
rs203145	6:138,615,148	A/G	—	benign
rs760554395	6:138,615,249	C/G	—	uncertain significance
rs2482583910	6:138,617,939	T/C	—	uncertain significance
rs753224287	6:138,617,994	C/T	—	uncertain significance
rs574284185	6:138,618,058	G/A	—	uncertain significance
rs6905283	6:138,618,099	A/C	—	benign
rs1317016668	6:138,619,789	T/G	—	uncertain significance
rs771535333	6:138,619,867	G/A	—	uncertain significance
rs1332033574	6:138,628,390	G/A	—	uncertain significance
rs778099059	6:138,628,472	A/C	—	uncertain significance
rs760841344	6:138,628,478	T/C	—	uncertain significance
rs995190061	6:138,628,494	G/C	—	uncertain significance
rs140836920	6:138,628,503	G/A	—	likely benign

Showing 100 of 163 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.