ARHGAP1
Rho GTPase activating protein 1
Summary
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012]
Known Variants33 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs775689729 | 11:46,700,606 | G/A | — | uncertain significance |
| rs765587887 | 11:46,700,648 | G/A | — | uncertain significance |
| rs2064503899 | 11:46,700,715 | G/A | — | uncertain significance |
| rs371098034 | 11:46,700,757 | G/C | — | uncertain significance |
| rs200846104 | 11:46,700,765 | T/C | — | uncertain significance |
| rs11822837 | 11:46,700,941 | G/A | — | likely benign |
| rs770285908 | 11:46,700,962 | C/T | — | uncertain significance |
| rs2064508345 | 11:46,701,216 | G/A | — | uncertain significance |
| rs758065311 | 11:46,701,310 | G/A | — | likely benign |
| rs144801476 | 11:46,702,070 | A/G | — | benign |
| rs2064517044 | 11:46,702,089 | C/T | — | likely benign |
| rs139663325 | 11:46,702,097 | G/T | — | uncertain significance |
| rs778417367 | 11:46,702,099 | T/A | — | uncertain significance |
| rs144522434 | 11:46,702,225 | G/T | — | benign |
| rs572555794 | 11:46,702,229 | G/T | — | uncertain significance |
| rs772140895 | 11:46,702,260 | C/A | — | uncertain significance |
| rs1237956979 | 11:46,702,270 | C/G | — | uncertain significance |
| rs751031172 | 11:46,702,291 | G/A | — | likely benign |
| rs566268205 | 11:46,702,633 | T/C | — | uncertain significance |
| rs151245025 | 11:46,702,853 | G/C | — | uncertain significance |
| rs2502743807 | 11:46,703,638 | T/A | — | uncertain significance |
| rs764362910 | 11:46,703,656 | C/T | — | uncertain significance |
| rs184204306 | 11:46,707,782 | C/T | intron variant | — |
| rs4603265 | 11:46,708,196 | C/G | — | — |
| rs537320455 | 11:46,709,742 | C/T | — | uncertain significance |
| rs1184658461 | 11:46,709,756 | G/A | — | uncertain significance |
| rs779690962 | 11:46,709,784 | T/C | — | uncertain significance |
| rs187474069 | 11:46,710,871 | A/C | intron variant | — |
| rs760960194 | 11:46,717,234 | G/A | — | conflicting classifications of pathogenicity |
| rs554016754 | 11:46,717,283 | C/T | — | benign |
| rs2502770791 | 11:46,717,581 | G/A | — | uncertain significance |
| rs747032432 | 11:46,717,650 | G/A | — | uncertain significance |
| rs7932354 | 11:46,722,221 | T/C | regulatory region variant | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.