ARHGAP32

Rho GTPase activating protein 32

Summary

RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]

Known Variants157 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs147546090	11:128,838,808	T/C	—	likely benign
rs116891747	11:128,838,850	A/G	—	likely benign
rs2497850385	11:128,838,860	G/A	—	uncertain significance
rs976965840	11:128,838,869	C/T	—	uncertain significance
rs145706821	11:128,838,874	C/T	—	likely benign
rs112106627	11:128,838,936	C/T	—	likely benign
rs1303700754	11:128,838,981	A/C	—	uncertain significance
rs781418129	11:128,838,998	T/C	—	uncertain significance
rs745323075	11:128,839,038	G/A	—	uncertain significance
rs770023243	11:128,839,049	T/A	—	uncertain significance
rs1591480216	11:128,839,051	G/A	—	likely benign
rs754398777	11:128,839,125	G/T	—	uncertain significance
rs139852631	11:128,839,126	G/T	—	likely benign
rs368720856	11:128,839,134	C/T	—	uncertain significance
rs1339565010	11:128,839,143	G/C	—	uncertain significance
rs3740829	11:128,839,156	T/C	—	benign
rs773163368	11:128,839,166	T/C	—	uncertain significance
rs2497856383	11:128,839,172	T/C	—	uncertain significance
rs771009084	11:128,839,210	C/A	—	uncertain significance
rs371331393	11:128,839,272	G/A	stop gained	—
rs78689455	11:128,839,276	G/A	—	likely benign
rs760677992	11:128,839,280	G/A	—	uncertain significance
rs140966757	11:128,839,373	G/A	—	uncertain significance
rs78856194	11:128,839,405	T/C	—	benign
rs768793563	11:128,839,505	G/T	—	uncertain significance
rs60847789	11:128,839,526	C/G	—	benign
rs138669502	11:128,839,602	C/T	—	uncertain significance
rs79505038	11:128,839,603	G/A	—	likely benign
rs532962432	11:128,839,625	T/C	—	uncertain significance
rs199633352	11:128,839,628	C/T	—	uncertain significance
rs141689602	11:128,839,657	A/G	—	benign
rs746253996	11:128,839,703	T/C	—	uncertain significance
rs147135511	11:128,839,713	C/T	—	uncertain significance
rs1269230638	11:128,839,722	C/T	—	uncertain significance
rs776020740	11:128,839,730	G/A	—	uncertain significance
rs535956698	11:128,839,799	C/T	—	uncertain significance
rs372360136	11:128,839,874	G/A	—	uncertain significance
rs775353964	11:128,839,899	C/T	—	uncertain significance
rs141030632	11:128,839,901	T/C	—	uncertain significance
rs79961242	11:128,839,932	G/A	—	benign
rs910991422	11:128,840,018	C/T	—	uncertain significance
rs183293077	11:128,840,026	G/A	—	likely benign
rs368884236	11:128,840,069	G/A	—	uncertain significance
rs569669527	11:128,840,087	T/C	—	uncertain significance
rs200701464	11:128,840,181	G/A	—	uncertain significance
rs1279800646	11:128,840,202	G/A	—	uncertain significance
rs146744767	11:128,840,221	T/C	—	likely benign
rs761064440	11:128,840,225	G/A	—	uncertain significance
rs2497871997	11:128,840,250	G/A	—	uncertain significance
rs567546669	11:128,840,296	C/T	—	likely benign
rs531130281	11:128,840,299	C/T	—	likely benign
rs550726710	11:128,840,333	G/C	—	uncertain significance
rs200206728	11:128,840,352	C/T	—	uncertain significance
rs749174548	11:128,840,363	G/C	—	uncertain significance
rs751121614	11:128,840,418	T/C	—	uncertain significance
rs147352978	11:128,840,476	C/G	—	uncertain significance
rs1331293329	11:128,840,522	T/G	—	uncertain significance
rs139373466	11:128,840,582	T/C	—	likely benign
rs1325519953	11:128,840,624	A/T	—	uncertain significance
rs142850285	11:128,840,628	C/T	—	conflicting classifications of pathogenicity
rs902850610	11:128,840,631	G/C	—	uncertain significance
rs774867129	11:128,840,642	G/C	—	uncertain significance
rs200597023	11:128,840,799	T/C	—	uncertain significance
rs552856918	11:128,840,855	G/A	—	likely benign
rs2497881714	11:128,840,858	G/A	—	uncertain significance
rs61734317	11:128,840,869	G/A	—	benign
rs61748829	11:128,840,872	A/G	—	benign
rs140367157	11:128,840,878	G/C	—	conflicting classifications of pathogenicity
rs530219324	11:128,840,894	C/T	—	uncertain significance
rs144145037	11:128,840,902	G/A	—	likely benign
rs111896362	11:128,840,906	C/T	—	uncertain significance
rs141250792	11:128,840,935	A/G	—	likely benign
rs775546546	11:128,840,960	G/A	—	uncertain significance
rs763252101	11:128,840,993	G/A	—	uncertain significance
rs1945356812	11:128,841,005	A/G	—	uncertain significance
rs760897254	11:128,842,431	G/A	—	uncertain significance
rs2497898224	11:128,842,434	G/A	—	uncertain significance
rs754266793	11:128,842,440	G/T	—	uncertain significance
rs116064946	11:128,842,607	G/A	—	benign
rs371060410	11:128,842,622	T/C	—	uncertain significance
rs112411848	11:128,842,716	A/G	—	benign
rs771511786	11:128,842,736	T/C	—	uncertain significance
rs139276969	11:128,842,742	C/T	—	likely benign
rs581258	11:128,842,873	C/T	—	benign
rs970185560	11:128,842,925	A/C	—	uncertain significance
rs34661752	11:128,842,940	T/C	—	benign
rs2497907609	11:128,843,015	C/T	—	uncertain significance
rs990760548	11:128,843,054	C/T	—	uncertain significance
rs374876936	11:128,843,072	G/T	—	uncertain significance
rs2497908799	11:128,843,076	T/C	—	uncertain significance
rs1296779648	11:128,843,112	T/C	—	uncertain significance
rs141213420	11:128,843,131	C/T	—	likely benign
rs1217633460	11:128,843,180	T/C	—	uncertain significance
rs776801494	11:128,843,253	G/A	—	uncertain significance
rs569522801	11:128,843,285	C/T	—	uncertain significance
rs150090842	11:128,843,295	C/T	—	uncertain significance
rs143245403	11:128,843,296	G/A	—	likely benign
rs1591486645	11:128,843,311	G/A	—	likely benign
rs1346853006	11:128,843,316	G/A	—	uncertain significance
rs761102484	11:128,844,088	G/T	—	uncertain significance

Showing 100 of 157 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.