ARHGEF17

Rho guanine nucleotide exchange factor 17

Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within actin cytoskeleton organization. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants146 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs376619433	11:73,019,707	C/G	—	likely benign
rs748621506	11:73,019,727	C/T	—	uncertain significance
rs747350488	11:73,019,778	A/G	—	uncertain significance
rs1052546299	11:73,019,804	C/T	—	uncertain significance
rs2495829781	11:73,019,813	T/A	—	uncertain significance
rs1225840589	11:73,019,883	C/A	—	uncertain significance
rs920266362	11:73,019,885	G/A	—	uncertain significance
rs758990617	11:73,019,897	C/T	—	uncertain significance
rs944923296	11:73,019,915	C/T	—	uncertain significance
rs892596178	11:73,019,922	C/T	—	uncertain significance
rs1864744234	11:73,019,943	G/A	—	uncertain significance
rs776749053	11:73,020,056	A/C	—	uncertain significance
rs1379353003	11:73,020,100	G/C	—	uncertain significance
rs2495831170	11:73,020,138	G/A	—	uncertain significance
rs754479898	11:73,020,161	C/A	—	uncertain significance
rs779001452	11:73,020,167	G/C	—	uncertain significance
rs756911360	11:73,020,208	A/C	—	likely benign
rs1256829425	11:73,020,221	G/A	—	uncertain significance
rs764949347	11:73,020,343	C/G	—	uncertain significance
rs774953746	11:73,020,359	G/A	—	uncertain significance
rs777173481	11:73,020,392	G/A	—	uncertain significance
rs147871402	11:73,020,399	C/A	—	benign
rs1407266069	11:73,020,518	G/A	—	uncertain significance
rs746332104	11:73,020,602	A/T	—	uncertain significance
rs1323313480	11:73,020,680	C/G	—	uncertain significance
rs142656646	11:73,020,686	G/A	—	uncertain significance
rs771690518	11:73,020,726	C/T	—	uncertain significance
rs150138024	11:73,020,782	G/A	—	uncertain significance
rs2495834715	11:73,020,806	G/C	—	uncertain significance
rs746535111	11:73,020,819	C/T	—	uncertain significance
rs370115261	11:73,020,836	G/T	—	uncertain significance
rs767867721	11:73,020,840	G/A	—	uncertain significance
rs200132734	11:73,020,845	C/T	—	likely benign
rs3741151	11:73,020,846	G/A	missense variant	—
rs201956060	11:73,020,853	C/A	—	conflicting classifications of pathogenicity
rs758793458	11:73,020,912	C/T	—	uncertain significance
rs374129335	11:73,020,933	G/A	—	uncertain significance
rs781505867	11:73,021,051	T/G	—	uncertain significance
rs774660799	11:73,021,067	C/G	—	uncertain significance
rs140950485	11:73,021,075	T/G	—	uncertain significance
rs369105191	11:73,021,083	T/C	—	uncertain significance
rs753459549	11:73,021,086	C/T	—	uncertain significance
rs764909190	11:73,021,217	G/A	—	uncertain significance
rs757903292	11:73,021,307	C/T	—	uncertain significance
rs1315104728	11:73,021,326	C/T	—	uncertain significance
rs1479139608	11:73,021,329	G/C	—	uncertain significance
rs140348469	11:73,021,338	A/G	—	uncertain significance
rs371062745	11:73,021,343	A/G	—	likely benign
rs763274361	11:73,021,352	C/T	—	uncertain significance
rs757353332	11:73,021,362	G/A	—	uncertain significance
rs201562229	11:73,021,367	A/G	—	likely benign
rs1864799712	11:73,021,416	C/T	—	uncertain significance
rs149321700	11:73,021,418	G/C	—	likely benign
rs149213151	11:73,021,494	G/A	—	conflicting classifications of pathogenicity
rs1242929591	11:73,021,574	C/T	—	uncertain significance
rs1864804736	11:73,021,592	T/G	—	uncertain significance
rs1042684194	11:73,021,628	G/C	—	uncertain significance
rs1329940867	11:73,021,629	G/A	—	uncertain significance
rs148112775	11:73,021,754	G/A	—	uncertain significance
rs1018751527	11:73,021,770	C/T	—	uncertain significance
rs369681028	11:73,021,802	C/T	—	uncertain significance
rs916287972	11:73,021,863	C/G	—	uncertain significance
rs200783173	11:73,021,866	G/C	—	uncertain significance
rs752637290	11:73,021,904	C/T	—	uncertain significance
rs146275379	11:73,022,016	G/T	—	uncertain significance
rs758488742	11:73,022,078	G/T	—	uncertain significance
rs151136328	11:73,022,129	G/A	—	uncertain significance
rs373763702	11:73,022,180	C/T	—	uncertain significance
rs370660401	11:73,022,292	G/A	—	likely benign
rs754685199	11:73,022,313	G/A	—	uncertain significance
rs769011649	11:73,022,362	G/A	—	likely benign
rs139353082	11:73,022,370	C/T	—	uncertain significance
rs765506319	11:73,022,389	C/G	—	uncertain significance
rs771434898	11:73,022,438	C/T	—	uncertain significance
rs759920014	11:73,022,442	G/A	—	uncertain significance
rs758564668	11:73,022,487	G/A	—	likely benign
rs147085966	11:73,022,495	G/A	—	uncertain significance
rs775779249	11:73,022,529	G/A	—	likely benign
rs138287979	11:73,022,535	G/A	—	uncertain significance
rs371309199	11:73,022,555	C/T	—	uncertain significance
rs1257429175	11:73,022,613	C/G	—	uncertain significance
rs1240404602	11:73,022,655	C/T	—	uncertain significance
rs141958792	11:73,022,689	G/A	—	likely benign
rs548377617	11:73,022,693	G/A	—	uncertain significance
rs377437143	11:73,022,732	G/A	—	uncertain significance
rs145994191	11:73,022,787	C/T	—	likely benign
rs376945309	11:73,022,828	G/A	—	uncertain significance
rs2027760	11:73,036,481	G/A	regulatory region variant	—
rs79038783	11:73,038,746	C/G	regulatory region variant	—
rs7933162	11:73,044,213	A/C	intron variant	—
rs74749711	11:73,052,839	A/T	intron variant	—
rs542912354	11:73,057,932	T/C	—	uncertain significance
rs147103857	11:73,057,987	G/A	—	likely benign
rs1374318119	11:73,063,907	C/G	—	uncertain significance
rs377281978	11:73,063,911	G/A	—	uncertain significance
rs771412159	11:73,063,947	G/C	—	uncertain significance
rs147573130	11:73,063,992	C/G	—	uncertain significance
rs200372043	11:73,064,056	C/T	—	uncertain significance
rs376468445	11:73,066,916	G/A	—	uncertain significance
rs774190875	11:73,067,280	C/T	—	uncertain significance

Showing 100 of 146 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.