ARID1B

AT-rich interaction domain 1B

Summary

This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Known Variants1,461 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1868252636:157,098,835G/A—likely benign
rs5661214936:157,099,013G/A—benign
rs10428750116:157,099,024T/G—likely benign
rs7970452666:157,099,061A/G—conflicting classifications of pathogenicity
rs21149567146:157,099,070C/T—uncertain significance
rs10151471376:157,099,072T/A—uncertain significance
rs10575186486:157,099,080G/Amissense variantpathogenic
rs7530143566:157,099,083C/G—uncertain significance
rs13519100386:157,099,085G/C—conflicting classifications of pathogenicity
rs9636396216:157,099,088G/A—benign
rs8672400496:157,099,089C/G—uncertain significance
rs7970452736:157,099,097G/A—conflicting classifications of pathogenicity
rs13702762876:157,099,106A/G—uncertain significance
rs12947082796:157,099,109G/A—uncertain significance
rs13383602906:157,099,114G/C—likely benign
rs25468163526:157,099,117C/A—uncertain significance
rs14653317966:157,099,118G/C—likely benign
rs12915730996:157,099,120C/T—likely benign
rs13197665366:157,099,125C/G—uncertain significance
rs25468165276:157,099,126C/A—likely benign
rs12128136136:157,099,127G/A—benign
rs5331827206:157,099,132G/A—likely benign
rs14752088516:157,099,139A/C—conflicting classifications of pathogenicity
rs9822186826:157,099,140A/C—likely benign
rs14039947716:157,099,144G/T—likely benign
rs9353206806:157,099,158C/G—likely benign
rs3716807916:157,099,160G/A—likely benign
rs13254144736:157,099,161C/T—conflicting classifications of pathogenicity
rs10575201406:157,099,164T/C—likely benign
rs7474811256:157,099,167C/T—benign
rs13311507766:157,099,174C/T—likely benign
rs9958630536:157,099,179C/T—likely benign
rs12108727566:157,099,182C/G—uncertain significance
rs12816273806:157,099,183C/T—likely benign
rs8902151016:157,099,185C/T—conflicting classifications of pathogenicity
rs11876998666:157,099,188C/G—uncertain significance
rs14737744766:157,099,192G/T—likely benign
rs21149607856:157,099,193G/T—uncertain significance
rs11576616156:157,099,195A/G—likely benign
rs14365341636:157,099,201G/T—likely benign
rs21149610966:157,099,202G/T—uncertain significance
rs13570907796:157,099,203C/T—benign
rs3754863866:157,099,209C/T—conflicting classifications of pathogenicity
rs7478654436:157,099,213C/G—likely benign
rs12199123886:157,099,216C/T—likely benign
rs13489327806:157,099,217T/G—conflicting classifications of pathogenicity
rs14848180396:157,099,221C/T—conflicting classifications of pathogenicity
rs7715462436:157,099,222G/C—likely benign
rs21149618236:157,099,224G/C—uncertain significance
rs11800679376:157,099,230G/A—uncertain significance
rs5556250596:157,099,231C/G—likely benign
rs14786144366:157,099,233C/T—uncertain significance
rs7726155766:157,099,235G/A—conflicting classifications of pathogenicity
rs7606154436:157,099,241G/C—likely benign
rs17787793116:157,099,242A/G—uncertain significance
rs3698871276:157,099,246G/C—likely benign
rs7767456186:157,099,260A/G—conflicting classifications of pathogenicity
rs25468191146:157,099,270G/A—likely benign
rs13316278576:157,099,275C/T—uncertain significance
rs12017261566:157,099,295G/A—uncertain significance
rs14647019966:157,099,302C/A—uncertain significance
rs14601038806:157,099,307C/A—conflicting classifications of pathogenicity
rs21149645446:157,099,308A/C—uncertain significance
rs12512415936:157,099,309G/A—likely benign
rs15623752026:157,099,314A/G—likely benign
rs3727262156:157,099,315C/G—likely benign
rs13912719386:157,099,316C/A—likely benign
rs10429766776:157,099,317A/G—uncertain significance
rs14403019346:157,099,327C/T—likely benign
rs7516121606:157,099,328C/T—likely benign
rs7573990766:157,099,329A/C—likely benign
rs13932815636:157,099,330T/C—likely benign
rs17787941196:157,099,332C/A—uncertain significance
rs5877797416:157,099,341A/T—likely benign
rs13012309456:157,099,342C/A—uncertain significance
rs3749890346:157,099,349C/A—likely benign
rs21149664516:157,099,354C/T—likely benign
rs5527965006:157,099,356A/G—uncertain significance
rs11886608776:157,099,359A/C—uncertain significance
rs17788036506:157,099,365A/G—likely benign
rs15623754696:157,099,366C/T—likely benign
rs14547322166:157,099,379C/G—uncertain significance
rs17788061026:157,099,385C/G—uncertain significance
rs25468219616:157,099,400T/C—uncertain significance
rs9054640156:157,099,402C/G—uncertain significance
rs13412566236:157,099,412C/G—likely benign
rs5447676106:157,099,417G/A—likely benign
rs13819539256:157,099,420G/A—likely benign
rs782531286:157,099,426A/G—likely benign
rs7716498176:157,099,432G/A—likely benign
rs12917613956:157,099,435G/A—likely benign
rs10227733366:157,099,438G/A—likely benign
rs9701004586:157,099,441G/A—likely benign
rs7773006416:157,099,444G/A—likely benign
rs7464664586:157,099,450A/G—likely benign
rs14251342856:157,099,453G/A—likely benign
rs14517689526:157,099,469A/G—uncertain significance
rs7696455556:157,099,470A/G—uncertain significance
rs25468241166:157,099,472A/G—uncertain significance
rs21149714206:157,099,474C/T—likely benign

Showing 100 of 1,461 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.