ARL11
ARF like GTPase 11
Summary
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010]
Known Variants18 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs552733858 | 13:50,203,001 | T/G | — | — |
| rs201791650 | 13:50,204,594 | T/A | — | uncertain significance |
| rs370668058 | 13:50,204,630 | T/C | — | uncertain significance |
| rs201132357 | 13:50,204,678 | T/G | — | uncertain significance |
| rs764419423 | 13:50,204,709 | C/T | — | likely benign |
| rs749892930 | 13:50,204,752 | G/A | — | uncertain significance |
| rs113027020 | 13:50,204,789 | C/T | — | uncertain significance |
| rs763436324 | 13:50,204,813 | A/G | — | uncertain significance |
| rs772293845 | 13:50,204,882 | C/T | — | likely benign |
| rs761431152 | 13:50,204,917 | A/G | — | uncertain significance |
| rs994780789 | 13:50,204,926 | G/A | — | uncertain significance |
| rs748581908 | 13:50,204,969 | C/T | — | uncertain significance |
| rs752737224 | 13:50,204,995 | A/G | — | uncertain significance |
| rs3803185 | 13:50,205,025 | T/G | missense variant | — |
| rs34301344 | 13:50,205,029 | A/G | — | likely benign |
| rs767279791 | 13:50,205,109 | C/T | — | uncertain significance |
| rs369303916 | 13:50,205,151 | C/T | — | uncertain significance |
| rs1441750086 | 13:50,205,164 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.