ARSD
arylsulfatase D
Summary
The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]
Known Variants57 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1211009840 | X:2,825,359 | G/A | — | uncertain significance |
| rs2228433 | X:2,825,363 | G/A | — | benign |
| rs201828808 | X:2,825,478 | G/T | — | uncertain significance |
| rs200785812 | X:2,825,479 | C/T | — | uncertain significance |
| rs2519472884 | X:2,825,496 | G/C | — | uncertain significance |
| rs747115406 | X:2,825,512 | G/A | — | uncertain significance |
| rs200569213 | X:2,825,581 | C/T | — | uncertain significance |
| rs2229557 | X:2,825,596 | C/T | — | benign |
| rs768877786 | X:2,825,626 | C/T | — | uncertain significance |
| rs192794144 | X:2,825,665 | C/T | — | uncertain significance |
| rs757272441 | X:2,826,765 | C/G | — | uncertain significance |
| rs2088876638 | X:2,826,786 | C/T | — | uncertain significance |
| rs138030490 | X:2,827,930 | C/T | — | benign |
| rs746453494 | X:2,827,976 | C/T | — | uncertain significance |
| rs139484145 | X:2,832,668 | A/G | — | likely benign |
| rs113031742 | X:2,832,696 | T/C | — | likely benign |
| rs73632953 | X:2,832,715 | T/C | — | likely benign |
| rs73632954 | X:2,832,787 | A/G | — | likely benign |
| rs111939179 | X:2,833,605 | C/T | — | likely benign |
| rs1240525630 | X:2,833,606 | A/C | — | uncertain significance |
| rs373216270 | X:2,833,628 | A/C | — | likely benign |
| rs377542415 | X:2,833,631 | A/G | — | likely benign |
| rs370769167 | X:2,833,638 | C/T | — | likely benign |
| rs115332247 | X:2,833,643 | C/A | — | likely benign |
| rs1354804234 | X:2,833,662 | G/A | — | uncertain significance |
| rs2519486895 | X:2,833,683 | A/G | — | uncertain significance |
| rs2519486930 | X:2,833,705 | G/C | — | likely benign |
| rs146636025 | X:2,833,720 | G/A | — | uncertain significance |
| rs78034736 | X:2,835,863 | G/T | — | likely benign |
| rs756337460 | X:2,835,935 | A/G | — | uncertain significance |
| rs143238998 | X:2,835,989 | A/C | — | likely benign |
| rs150899882 | X:2,835,995 | C/A | — | likely benign |
| rs211653 | X:2,836,037 | G/C | — | benign |
| rs67272620 | X:2,836,041 | A/T | — | likely benign |
| rs67359049 | X:2,836,047 | C/T | — | likely benign |
| rs1488292276 | X:2,836,065 | C/G | — | uncertain significance |
| rs373076877 | X:2,836,093 | C/A | — | uncertain significance |
| rs747015336 | X:2,836,097 | G/T | — | uncertain significance |
| rs376322458 | X:2,836,115 | G/A | — | uncertain significance |
| rs2088988479 | X:2,836,164 | T/G | — | uncertain significance |
| rs73632975 | X:2,836,181 | A/T | — | likely benign |
| rs73632976 | X:2,836,184 | C/T | — | likely benign |
| rs73632977 | X:2,836,211 | A/T | — | likely benign |
| rs73632978 | X:2,836,238 | G/A | — | likely benign |
| rs1453802640 | X:2,836,266 | T/G | — | uncertain significance |
| rs759669373 | X:2,838,756 | C/T | — | uncertain significance |
| rs151213601 | X:2,840,009 | G/A | — | uncertain significance |
| rs1378195046 | X:2,840,052 | C/T | — | uncertain significance |
| rs754641237 | X:2,840,060 | G/A | — | uncertain significance |
| rs1637781 | X:2,843,139 | T/G | — | — |
| rs1200074059 | X:2,843,673 | C/T | — | uncertain significance |
| rs1386167342 | X:2,843,709 | C/T | — | uncertain significance |
| rs759116005 | X:2,843,762 | G/A | — | uncertain significance |
| rs202070019 | X:2,843,789 | A/G | — | uncertain significance |
| rs975306385 | X:2,847,291 | C/T | — | uncertain significance |
| rs2518304981 | X:2,847,310 | A/G | — | uncertain significance |
| rs6567682 | X:2,848,409 | T/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.