ASB10

ankyrin repeat and SOCS box containing 10

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]

Known Variants139 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs310597	7:150,873,046	G/A	—	benign
rs1801381446	7:150,873,217	A/C	—	uncertain significance
rs3800791	7:150,873,246	G/A	—	benign
rs935737499	7:150,873,251	G/A	—	uncertain significance
rs1255332685	7:150,873,284	C/A	—	uncertain significance
rs104886487	7:150,873,285	T/C	—	not provided
rs764929940	7:150,873,297	G/T	—	conflicting classifications of pathogenicity
rs143907990	7:150,873,303	G/A	—	uncertain significance
rs104886486	7:150,873,331	C/T	—	likely benign
rs566879250	7:150,873,338	G/C	—	uncertain significance
rs777336890	7:150,873,357	A/G	—	uncertain significance
rs4726004	7:150,873,566	C/T	—	likely benign
rs310598	7:150,873,608	A/G	—	benign
rs73478620	7:150,873,624	C/G	—	likely benign
rs919533	7:150,873,664	G/T	—	benign
rs1280598642	7:150,873,671	C/A	—	likely benign
rs770356435	7:150,873,679	C/T	—	uncertain significance
rs959800416	7:150,873,700	C/T	—	likely benign
rs1801394581	7:150,873,713	G/A	—	likely benign
rs564809133	7:150,873,728	G/C	—	uncertain significance
rs973068070	7:150,873,730	T/A	—	uncertain significance
rs61628535	7:150,873,736	G/A	—	benign
rs62489646	7:150,873,754	A/G	—	benign
rs891508	7:150,877,774	A/G	—	benign
rs62489648	7:150,877,806	C/T	—	benign
rs67235637	7:150,877,882	A/G	—	benign
rs104886485	7:150,878,034	G/A	—	uncertain significance
rs151344614	7:150,878,038	C/A	—	not provided
rs765065592	7:150,878,039	C/A	—	uncertain significance
rs151344612	7:150,878,051	C/T	—	not provided
rs104886484	7:150,878,052	G/A	—	benign
rs201566253	7:150,878,055	C/T	—	benign
rs201589795	7:150,878,058	C/T	—	uncertain significance
rs151344611	7:150,878,064	G/A	—	not provided
rs104886483	7:150,878,084	A/G	—	uncertain significance
rs139613280	7:150,878,094	G/A	—	uncertain significance
rs767616564	7:150,878,101	G/A	—	likely benign
rs61734407	7:150,878,106	G/A	—	benign
rs755450741	7:150,878,122	C/G	—	uncertain significance
rs104886482	7:150,878,134	G/C	—	not provided
rs104886481	7:150,878,144	G/A	—	likely benign
rs151344610	7:150,878,172	C/T	—	not provided
rs139263114	7:150,878,202	C/T	—	uncertain significance
rs144099189	7:150,878,203	G/A	—	likely benign
rs867566791	7:150,878,219	C/T	—	uncertain significance
rs61735130	7:150,878,220	G/A	—	benign
rs104886479	7:150,878,222	C/T	—	not provided
rs774168463	7:150,878,223	G/A	—	uncertain significance
rs149064245	7:150,878,244	G/A	—	likely benign
rs151344609	7:150,878,246	T/A	—	not provided
rs781304410	7:150,878,258	T/C	—	uncertain significance
rs2253592	7:150,878,260	C/G	—	benign
rs879144101	7:150,878,261	G/A	—	uncertain significance
rs1300802233	7:150,878,271	C/T	—	uncertain significance
rs2485640388	7:150,878,274	C/T	—	uncertain significance
rs2485640480	7:150,878,304	G/T	—	uncertain significance
rs140602973	7:150,878,315	C/T	—	not provided
rs104886478	7:150,878,320	G/A	synonymous variant	not provided
rs61743170	7:150,878,332	A/G	—	benign
rs372100256	7:150,878,392	G/A	—	benign
rs104886477	7:150,878,393	G/T	—	uncertain significance
rs104886476	7:150,878,399	C/T	—	benign
rs104886475	7:150,878,416	C/T	—	benign
rs61735708	7:150,878,421	G/C	—	likely benign
rs151344613	7:150,878,502	G/T	—	not provided
rs104886474	7:150,878,511	C/G	missense variant	pathogenic
rs151344607	7:150,878,540	G/A	—	not provided
rs114020455	7:150,878,549	T/C	—	benign
rs4726006	7:150,878,803	G/A	—	benign
rs4725396	7:150,878,845	T/G	—	benign
rs4725397	7:150,878,860	C/T	—	benign
rs2257069	7:150,883,221	G/A	—	benign
rs10274484	7:150,883,226	G/A	—	benign
rs2257073	7:150,883,287	C/T	—	benign
rs1185990188	7:150,883,489	C/T	—	uncertain significance
rs191851268	7:150,883,492	G/T	—	conflicting classifications of pathogenicity
rs104886473	7:150,883,498	G/A	—	likely benign
rs151344606	7:150,883,499	G/T	stop gained	not provided
rs151344605	7:150,883,516	G/A	—	not provided
rs1801592410	7:150,883,517	T/A	—	uncertain significance
rs766462847	7:150,883,534	C/T	—	uncertain significance
rs104886472	7:150,883,539	T/G	—	not provided
rs757429484	7:150,883,546	C/T	—	uncertain significance
rs104886471	7:150,883,547	G/A	—	benign
rs151344604	7:150,883,548	G/C	—	uncertain significance
rs1171763315	7:150,883,549	C/T	—	uncertain significance
rs376305207	7:150,883,551	C/T	—	uncertain significance
rs104886470	7:150,883,576	A/T	—	uncertain significance
rs1801595116	7:150,883,585	G/A	—	uncertain significance
rs77615410	7:150,883,593	G/A	—	benign
rs139505650	7:150,883,603	C/T	—	uncertain significance
rs370599172	7:150,883,612	C/T	—	uncertain significance
rs73727103	7:150,883,613	G/A	—	likely benign
rs199709285	7:150,883,651	G/A	—	uncertain significance
rs767765146	7:150,883,665	C/T	—	conflicting classifications of pathogenicity
rs201535252	7:150,883,671	A/G	—	likely benign
rs1041561810	7:150,883,713	G/T	—	uncertain significance
rs2150560614	7:150,883,736	A/G	—	likely benign
rs146931238	7:150,883,742	G/C	—	benign
rs2257090	7:150,883,761	C/T	—	benign

Showing 100 of 139 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.