ASB3
ankyrin repeat and SOCS box containing 3
Summary
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2011]
Known Variants7 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11553661 | 2:53,921,056 | C/T | — | uncertain significance |
| rs764897074 | 2:53,941,575 | T/C | — | uncertain significance |
| rs750182921 | 2:53,941,620 | T/C | — | uncertain significance |
| rs2009144 | 2:53,944,363 | G/A | intron variant | — |
| rs58359565 | 2:53,958,919 | C/T | — | — |
| rs2692530 | 2:54,002,503 | T/A | downstream gene variant | — |
| rs2542582 | 2:54,003,013 | C/G | downstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.