ASB4
ankyrin repeat and SOCS box containing 4
Summary
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008]
Known Variants36 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs117228167 | 7:95,103,233 | A/G | coding sequence variant | — |
| rs184557318 | 7:95,103,335 | A/G | upstream gene variant | — |
| rs145919755 | 7:95,110,060 | C/T | intron variant | — |
| rs373298545 | 7:95,115,320 | G/A | — | uncertain significance |
| rs1562808164 | 7:95,115,336 | A/C | — | uncertain significance |
| rs560803372 | 7:95,115,366 | A/G | — | uncertain significance |
| rs1554346305 | 7:95,115,442 | G/T | — | uncertain significance |
| rs775225728 | 7:95,115,455 | G/A | — | uncertain significance |
| rs185489033 | 7:95,116,041 | C/G | intron variant | — |
| rs764528090 | 7:95,125,103 | C/T | — | uncertain significance |
| rs746653735 | 7:95,125,149 | A/C | — | uncertain significance |
| rs757962480 | 7:95,125,238 | A/G | — | uncertain significance |
| rs751022766 | 7:95,125,327 | A/G | — | uncertain significance |
| rs199681056 | 7:95,131,701 | T/G | — | — |
| rs139162949 | 7:95,138,556 | T/A | regulatory region variant | — |
| rs544430450 | 7:95,153,449 | G/A | — | — |
| rs182232687 | 7:95,153,629 | C/A | intron variant | — |
| rs763813324 | 7:95,157,155 | A/G | — | uncertain significance |
| rs1225982392 | 7:95,157,181 | G/A | — | uncertain significance |
| rs771285372 | 7:95,157,228 | C/G | — | uncertain significance |
| rs2484741791 | 7:95,157,329 | A/C | — | uncertain significance |
| rs367544749 | 7:95,157,401 | C/G | — | uncertain significance |
| rs772632934 | 7:95,157,432 | C/A | — | uncertain significance |
| rs765506289 | 7:95,157,479 | T/C | — | uncertain significance |
| rs770804094 | 7:95,157,532 | C/T | — | uncertain significance |
| rs775399940 | 7:95,157,550 | G/A | — | uncertain significance |
| rs750696626 | 7:95,157,563 | A/G | — | uncertain significance |
| rs2484754482 | 7:95,165,765 | A/G | — | uncertain significance |
| rs772366404 | 7:95,165,845 | C/A | — | uncertain significance |
| rs2484754780 | 7:95,165,855 | A/G | — | uncertain significance |
| rs140805293 | 7:95,166,890 | G/T | — | uncertain significance |
| rs142735600 | 7:95,166,923 | G/A | — | uncertain significance |
| rs1268681871 | 7:95,166,988 | T/A | — | uncertain significance |
| rs201104760 | 7:95,167,040 | T/C | — | uncertain significance |
| rs757210569 | 7:95,167,063 | A/G | — | uncertain significance |
| rs540495505 | 7:95,167,808 | A/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.