ASNS

asparagine synthetase (glutamine-hydrolyzing)

Summary

The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

Known Variants563 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs115270247	7:97,481,491	T/G	—	benign
rs775200046	7:97,481,571	C/T	—	likely benign
rs760440838	7:97,481,583	A/G	—	likely benign
rs2115580763	7:97,481,589	C/T	—	likely benign
rs2115580810	7:97,481,591	T/A	—	uncertain significance
rs2115580987	7:97,481,598	G/T	—	likely benign
rs1430382146	7:97,481,604	C/T	—	likely benign
rs532710533	7:97,481,605	G/A	—	uncertain significance
rs552452349	7:97,481,608	C/T	—	pathogenic
rs398122974	7:97,481,609	G/A	missense variant	pathogenic
rs897877891	7:97,481,619	G/T	—	uncertain significance
rs2115581448	7:97,481,622	A/G	—	likely benign
rs1584455576	7:97,481,625	G/C	—	likely benign
rs1562811035	7:97,481,627	C/T	—	uncertain significance
rs751735389	7:97,481,629	T/C	—	uncertain significance
rs1584455597	7:97,481,631	G/A	—	likely benign
rs2484622880	7:97,481,636	A/T	—	uncertain significance
rs2484622907	7:97,481,639	T/C	—	uncertain significance
rs1182799813	7:97,481,641	G/A	—	uncertain significance
rs767700335	7:97,481,643	C/T	missense variant	pathogenic
rs752951804	7:97,481,647	C/T	—	pathogenic
rs2115581844	7:97,481,648	A/C	—	uncertain significance
rs2484622997	7:97,481,652	A/G	—	likely benign
rs201432154	7:97,481,664	G/T	—	conflicting classifications of pathogenicity
rs993460441	7:97,481,665	T/C	—	uncertain significance
rs140975053	7:97,481,670	C/T	—	likely benign
rs757715023	7:97,481,671	C/T	—	uncertain significance
rs2484623300	7:97,481,676	T/C	—	likely benign
rs201209327	7:97,481,679	G/T	—	likely pathogenic
rs771595135	7:97,481,682	A/G	—	likely benign
rs373078034	7:97,481,687	G/T	—	uncertain significance
rs746606098	7:97,481,695	A/C	—	uncertain significance
rs2484623496	7:97,481,697	T/C	—	likely benign
rs2115582511	7:97,481,700	A/C	—	likely benign
rs568570377	7:97,481,701	C/T	missense variant	pathogenic
rs1251417315	7:97,481,702	G/A	—	uncertain significance
rs1347461167	7:97,481,703	G/A	—	likely benign
rs2484623572	7:97,481,706	G/A	—	likely benign
rs2115582682	7:97,481,715	T/C	—	likely benign
rs2484623660	7:97,481,721	G/A	—	likely benign
rs761677126	7:97,481,722	G/T	—	uncertain significance
rs2115582763	7:97,481,724	T/C	—	likely benign
rs773279607	7:97,481,727	A/G	—	likely benign
rs2115582880	7:97,481,730	A/T	—	likely benign
rs372844492	7:97,481,748	C/G	—	uncertain significance
rs764468161	7:97,481,751	G/C	—	likely benign
rs2115583161	7:97,481,752	G/A	—	uncertain significance
rs1324747469	7:97,481,766	C/T	—	uncertain significance
rs376090391	7:97,481,767	A/G	—	uncertain significance
rs2115583452	7:97,481,769	T/C	—	likely benign
rs147448684	7:97,481,775	A/G	—	likely benign
rs779451673	7:97,481,783	G/A	—	uncertain significance
rs2484624290	7:97,481,786	A/C	—	likely benign
rs2115583693	7:97,481,787	G/C	—	likely benign
rs1461854812	7:97,481,789	A/G	—	likely benign
rs2484624377	7:97,481,792	A/T	—	likely benign
rs750880787	7:97,481,793	G/A	—	likely benign
rs1243612145	7:97,481,794	C/T	—	likely benign
rs913657474	7:97,481,796	T/C	—	likely benign
rs1562811397	7:97,481,797	A/G	—	likely benign
rs2484624470	7:97,481,798	T/G	—	likely benign
rs2484624478	7:97,481,799	A/G	—	likely benign
rs10486011	7:97,481,812	C/T	—	benign
rs17344752	7:97,481,926	A/G	—	benign
rs144971139	7:97,482,121	T/C	—	likely benign
rs6959868	7:97,482,207	G/A	—	benign
rs2484627920	7:97,482,358	T/C	—	likely benign
rs773038158	7:97,482,367	T/C	—	uncertain significance
rs1360370266	7:97,482,368	A/T	—	uncertain significance
rs1791258447	7:97,482,371	C/T	—	pathogenic
rs2484628083	7:97,482,374	G/A	—	pathogenic
rs762882170	7:97,482,376	T/C	—	uncertain significance
rs772079299	7:97,482,383	C/T	—	conflicting classifications of pathogenicity
rs768064875	7:97,482,384	G/A	—	conflicting classifications of pathogenicity
rs2115590472	7:97,482,389	C/G	—	uncertain significance
rs1791259662	7:97,482,392	G/A	—	pathogenic
rs1791259967	7:97,482,399	C/T	—	likely benign
rs754043007	7:97,482,409	G/A	missense variant	pathogenic
rs1224112605	7:97,482,414	C/T	—	likely benign
rs1791261153	7:97,482,421	G/T	—	pathogenic
rs1085307956	7:97,482,424	G/T	missense variant	pathogenic
rs1791261567	7:97,482,429	T/G	—	likely benign
rs1335991893	7:97,482,432	A/G	—	likely benign
rs2484628569	7:97,482,435	A/G	—	likely benign
rs1791266639	7:97,482,437	T/C	—	uncertain significance
rs1265172509	7:97,482,438	G/A	—	likely benign
rs750924344	7:97,482,441	G/A	—	likely benign
rs758889608	7:97,482,454	C/T	—	uncertain significance
rs373774032	7:97,482,455	G/A	—	pathogenic
rs1404048496	7:97,482,458	A/G	—	uncertain significance
rs2484628839	7:97,482,462	A/G	—	likely benign
rs139318320	7:97,482,483	G/A	—	likely benign
rs61733327	7:97,482,484	G/A	—	conflicting classifications of pathogenicity
rs145582437	7:97,482,495	C/T	—	likely benign
rs1230123411	7:97,482,496	G/C	—	likely pathogenic
rs2484629260	7:97,482,500	C/G	—	uncertain significance
rs2484629307	7:97,482,506	G/A	—	likely benign
rs749209281	7:97,482,512	G/A	—	uncertain significance
rs774128083	7:97,482,522	C/G	—	likely benign
rs760800612	7:97,482,526	T/C	—	uncertain significance

Showing 100 of 563 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.