BAZ2A

bromodomain adjacent to zinc finger domain 2A

Summary

Enables histone binding activity. Contributes to RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation; negative regulation of transcription by RNA polymerase I; and rDNA heterochromatin formation. Predicted to act upstream of or within heterochromatin formation. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants100 total

rsidPosition (GRCh37)AllelesClassClinVar
rs74596541412:56,992,409T/C—uncertain significance
rs37686671212:56,992,412G/C—uncertain significance
rs188607868712:56,992,443G/A—uncertain significance
rs254750802912:56,992,460C/T—uncertain significance
rs15111010612:56,992,501G/A—likely benign
rs254750989912:56,992,704T/G—uncertain significance
rs75397818712:56,992,707T/C—uncertain significance
rs76521573612:56,992,746C/G—uncertain significance
rs134108418212:56,992,949G/A—uncertain significance
rs254751336612:56,992,983C/T—uncertain significance
rs76305944612:56,992,988G/A—uncertain significance
rs74626615412:56,993,040G/A—uncertain significance
rs76880152012:56,993,046G/A—uncertain significance
rs254751538612:56,993,105G/C—uncertain significance
rs75614413512:56,993,754G/C—uncertain significance
rs36814612212:56,993,798G/C—uncertain significance
rs76212905812:56,993,834C/T—uncertain significance
rs75370926612:56,993,858T/C—likely benign
rs254752489612:56,993,875T/C—uncertain significance
rs188631540812:56,994,024C/T—uncertain significance
rs138361183512:56,994,075C/T—uncertain significance
rs76081389212:56,994,153C/T—uncertain significance
rs75262358212:56,994,181G/A—uncertain significance
rs75012043012:56,994,467G/A—uncertain significance
rs254753263912:56,994,497G/T—uncertain significance
rs37667519312:56,994,575C/A—uncertain significance
rs76810927312:56,994,774T/C—likely benign
rs100605093712:56,994,810C/T—uncertain significance
rs37748809112:56,995,016T/A—uncertain significance
rs75031460412:56,995,080G/A—uncertain significance
rs77974616312:56,995,104C/A—uncertain significance
rs124434152512:56,995,158C/A—uncertain significance
rs87934814312:56,995,174T/G—uncertain significance
rs86884498312:56,995,346A/G—likely benign
rs77479826412:56,995,356G/A—uncertain significance
rs37243252612:56,995,393C/T—likely benign
rs75106804212:56,995,452G/C—uncertain significance
rs19988660912:56,995,647G/C—uncertain significance
rs188651634112:56,995,664A/G—uncertain significance
rs19021637812:56,995,775C/T—uncertain significance
rs254754944612:56,995,890T/C—uncertain significance
rs75199972312:56,995,896T/C—likely benign
rs78140417412:56,995,898G/A—uncertain significance
rs54435287112:56,996,556C/T—uncertain significance
rs75277307712:56,996,593G/A—uncertain significance
rs132253391212:56,996,635G/C—uncertain significance
rs36879270412:56,997,165C/T—uncertain significance
rs76895233512:56,997,306C/T—uncertain significance
rs123034432512:56,997,371A/G—uncertain significance
rs74964950212:56,997,374C/G—uncertain significance
rs75367008312:56,997,411G/A—uncertain significance
rs76957372912:56,998,049A/G—uncertain significance
rs123601175412:56,998,053T/C—uncertain significance
rs20224700912:56,998,430G/T—uncertain significance
rs133658718812:56,998,979T/C—uncertain significance
rs142503292712:56,999,017C/T—uncertain significance
rs18983478812:56,999,457C/Tintron variant—
rs75017203112:56,999,685G/A—uncertain significance
rs254759113012:56,999,706T/C—uncertain significance
rs104471157512:56,999,752C/G—uncertain significance
rs20079522112:57,000,084G/C—uncertain significance
rs20042733112:57,003,547G/A—uncertain significance
rs195050271512:57,003,549T/C—uncertain significance
rs195050458612:57,003,615T/C—uncertain significance
rs54481991712:57,003,714T/G—uncertain significance
rs254763270412:57,003,717A/G—uncertain significance
rs213697671312:57,003,925A/C—uncertain significance
rs75805303912:57,003,969G/A—uncertain significance
rs36901305512:57,003,984C/G—uncertain significance
rs254763922912:57,004,247G/A—likely benign
rs77691759212:57,004,273C/T—uncertain significance
rs75967517912:57,004,278T/C—uncertain significance
rs37693148212:57,004,284C/T—uncertain significance
rs195056083712:57,005,417C/T—uncertain significance
rs254765246012:57,005,608T/G—uncertain significance
rs37503285412:57,005,667G/T—uncertain significance
rs77205227712:57,005,712G/A—uncertain significance
rs76542798212:57,005,761G/C—uncertain significance
rs54684007112:57,005,797T/A—uncertain significance
rs77529728612:57,005,806C/T—uncertain significance
rs123834503112:57,005,940G/A—uncertain significance
rs77349634612:57,006,876G/A—uncertain significance
rs144910685812:57,006,891G/C—uncertain significance
rs74861761912:57,007,782T/C—uncertain significance
rs19982462412:57,007,788T/C—uncertain significance
rs119480501712:57,007,832C/T—uncertain significance
rs36772565412:57,007,836C/T—uncertain significance
rs148910349612:57,008,857A/G—uncertain significance
rs77643744412:57,008,971G/C—uncertain significance
rs76805385112:57,008,998A/T—uncertain significance
rs55720211912:57,008,999T/C—uncertain significance
rs76167470712:57,009,110G/A—uncertain significance
rs75341315412:57,009,227G/A—likely benign
rs76874719712:57,009,367T/C—uncertain significance
rs254769370212:57,011,196A/T—uncertain significance
rs98612196712:57,011,220T/C—uncertain significance
rs36966135612:57,011,223A/G—uncertain significance
rs76256313712:57,011,265G/A—uncertain significance
rs797361812:57,019,443T/Cintron variant—
rs94120712:57,023,284C/A——

Gene information from NCBI Gene. Variant classifications from ClinVar.