CADM3
cell adhesion molecule 3
Summary
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016]
Known Variants33 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs757529773 | 1:159,141,605 | G/A | — | uncertain significance |
| rs894438762 | 1:159,141,628 | A/C | — | uncertain significance |
| rs2249581 | 1:159,144,581 | T/C | upstream gene variant | — |
| rs2249872 | 1:159,146,937 | A/T | regulatory region variant | — |
| rs3026968 | 1:159,147,452 | C/A | — | — |
| rs1474747 | 1:159,148,513 | C/A | — | — |
| rs2253837 | 1:159,156,296 | C/T | intron variant | — |
| rs267598112 | 1:159,161,729 | G/A | — | uncertain significance |
| rs2525592878 | 1:159,161,735 | C/T | — | uncertain significance |
| rs772051000 | 1:159,161,737 | T/C | — | uncertain significance |
| rs201884647 | 1:159,161,773 | G/A | — | uncertain significance |
| rs764210672 | 1:159,161,797 | G/A | — | uncertain significance |
| rs140248716 | 1:159,161,832 | T/G | — | likely benign |
| rs1299214820 | 1:159,162,398 | C/T | — | uncertain significance |
| rs748945624 | 1:159,162,404 | C/T | — | uncertain significance |
| rs369946971 | 1:159,162,508 | G/A | — | uncertain significance |
| rs193920866 | 1:159,162,520 | G/C | — | uncertain significance |
| rs2102125471 | 1:159,163,243 | A/G | — | likely pathogenic |
| rs770218887 | 1:159,163,248 | T/C | — | uncertain significance |
| rs1021719284 | 1:159,163,257 | C/T | — | uncertain significance |
| rs2525599465 | 1:159,163,297 | G/A | — | uncertain significance |
| rs751691830 | 1:159,163,662 | G/A | — | uncertain significance |
| rs763585215 | 1:159,163,734 | A/G | — | uncertain significance |
| rs1649786188 | 1:159,163,758 | A/G | — | uncertain significance |
| rs752968520 | 1:159,163,761 | G/A | — | uncertain significance |
| rs138200155 | 1:159,166,182 | C/A | — | conflicting classifications of pathogenicity |
| rs1649893771 | 1:159,166,191 | T/A | — | uncertain significance |
| rs1198767978 | 1:159,166,196 | G/A | — | uncertain significance |
| rs142955742 | 1:159,169,579 | G/A | — | uncertain significance |
| rs1224156115 | 1:159,169,588 | G/T | — | uncertain significance |
| rs199545197 | 1:159,169,649 | A/G | — | uncertain significance |
| rs779900801 | 1:159,170,608 | C/A | — | uncertain significance |
| rs761014332 | 1:159,170,642 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.