CCDC57

coiled-coil domain containing 57

Summary

Involved in several processes, including G2/M transition of mitotic cell cycle; cilium assembly; and microtubule cytoskeleton organization. Located in centriolar satellite; centriole; and spindle microtubule. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants73 total

rsidPosition (GRCh37)AllelesClassClinVar
rs112767817:80,059,487C/Tupstream gene variant—
rs36818606517:80,059,565A/G—uncertain significance
rs77837334917:80,059,597C/A—uncertain significance
rs37291000417:80,059,628C/T—uncertain significance
rs250985861317:80,059,670T/G—uncertain significance
rs139807765117:80,059,717G/T—uncertain significance
rs1165063317:80,083,807T/Cintron variant—
rs37674746717:80,085,696G/C—uncertain significance
rs54895956717:80,085,714G/C—likely benign
rs75977724817:80,086,385G/T—uncertain significance
rs462578317:80,086,395T/Cmissense variant—
rs37063788617:80,086,442G/A—uncertain significance
rs19186643817:80,086,470C/T—uncertain significance
rs1260232017:80,104,762C/Tregulatory region variant—
rs7137507417:80,107,917T/G——
rs20000550417:80,115,764G/C—uncertain significance
rs54676143217:80,115,776G/C—uncertain significance
rs74642503717:80,115,797C/T—likely benign
rs37251679117:80,115,824C/T—uncertain significance
rs807810217:80,117,478C/G——
rs37720805217:80,121,126C/T—uncertain significance
rs75548478017:80,121,168G/T—uncertain significance
rs121794858917:80,121,179C/T—uncertain significance
rs20195422617:80,121,207C/T—uncertain significance
rs20093835417:80,129,601C/T—uncertain significance
rs76351635617:80,129,620A/T—uncertain significance
rs145743031517:80,129,647C/G—uncertain significance
rs86837614617:80,129,661G/T—uncertain significance
rs18413286317:80,129,708G/C—likely benign
rs76181514217:80,130,669C/T—likely benign
rs78019461917:80,136,394C/T—likely benign
rs57398072917:80,136,450G/A—uncertain significance
rs36945067017:80,137,012T/A—uncertain significance
rs76783041917:80,137,015C/T—uncertain significance
rs20073189417:80,137,023G/T—uncertain significance
rs393581617:80,137,173C/Tintron variant—
rs55770854717:80,141,803C/T—uncertain significance
rs720794717:80,145,291A/Tintron variant—
rs121408294917:80,146,102T/C—uncertain significance
rs20150480917:80,146,154G/C—likely benign
rs75169344817:80,146,162C/A—uncertain significance
rs37316392317:80,146,215T/A—uncertain significance
rs118248797717:80,146,220C/G—uncertain significance
rs116315248217:80,146,221T/A—uncertain significance
rs37528830517:80,146,244C/T—likely benign
rs141840217917:80,146,261C/T—uncertain significance
rs20145804117:80,146,295C/G—uncertain significance
rs20163356817:80,151,859G/A—uncertain significance
rs77471147617:80,151,865G/A—likely benign
rs37657189217:80,151,895C/T—uncertain significance
rs88631182917:80,151,939T/C—uncertain significance
rs75218445617:80,151,969G/A—uncertain significance
rs19193891917:80,153,150G/A—uncertain significance
rs53287406117:80,153,195C/T—uncertain significance
rs76702993617:80,153,219A/G—uncertain significance
rs3510423117:80,154,787C/Tintron variant—
rs413277517:80,155,412C/A——
rs76031046617:80,156,221T/C—uncertain significance
rs36926685617:80,156,269C/T—uncertain significance
rs75667681917:80,156,279C/T—uncertain significance
rs76768515217:80,159,438C/T—uncertain significance
rs76095140917:80,159,439G/A—uncertain significance
rs36820900917:80,159,541C/G—uncertain significance
rs77700859817:80,159,555C/T—likely benign
rs75993198417:80,159,556G/A—uncertain significance
rs77979863717:80,159,586C/T—uncertain significance
rs105456792817:80,159,707G/C—uncertain significance
rs37046070117:80,159,738C/T—uncertain significance
rs76983247817:80,159,747T/A—uncertain significance
rs57296194017:80,159,775G/A—uncertain significance
rs20134158617:80,159,808C/G—uncertain significance
rs721885717:80,161,000T/Cintron variant—
rs424735717:80,166,989G/Tintron variant—

Gene information from NCBI Gene. Variant classifications from ClinVar.