CCL14
C-C motif chemokine ligand 14
Summary
This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]
Known Variants9 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142032662 | 17:34,310,539 | C/T | upstream gene variant | — |
| rs41341749 | 17:34,310,702 | A/G | upstream gene variant | — |
| rs778815719 | 17:34,311,381 | C/T | — | uncertain significance |
| rs375335603 | 17:34,311,392 | C/T | — | uncertain significance |
| rs769854730 | 17:34,311,485 | C/T | — | uncertain significance |
| rs185259562 | 17:34,313,481 | A/G | upstream gene variant | — |
| rs779464556 | 17:34,313,673 | C/T | — | likely benign |
| rs113937434 | 17:34,313,674 | G/A | synonymous variant | — |
| rs535658859 | 17:34,314,616 | T/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.