CCL15
C-C motif chemokine ligand 15
Summary
This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]
Known Variants14 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs774354664 | 17:34,324,807 | A/G | — | uncertain significance |
| rs1481732126 | 17:34,324,808 | T/C | — | uncertain significance |
| rs1285897220 | 17:34,324,829 | T/G | — | uncertain significance |
| rs745762672 | 17:34,324,876 | C/T | — | likely benign |
| rs138739843 | 17:34,324,877 | G/A | — | uncertain significance |
| rs41356845 | 17:34,325,248 | G/A | — | — |
| rs148926598 | 17:34,325,326 | G/T | missense variant | — |
| rs567687330 | 17:34,325,361 | T/C | — | uncertain significance |
| rs138438750 | 17:34,325,828 | G/A | upstream gene variant | — |
| rs141810667 | 17:34,325,940 | A/G | — | uncertain significance |
| rs368254487 | 17:34,328,519 | C/T | — | uncertain significance |
| rs184763496 | 17:34,328,980 | G/A | regulatory region variant | — |
| rs544570071 | 17:34,329,216 | C/T | — | — |
| rs854628 | 17:34,329,822 | C/A | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.