CCL15-CCL14

CCL15-CCL14 readthrough (NMD candidate)

Summary

A cluster of CC chemokine genes exists on chromosome 17q11.2. The CC chemokines are secreted proteins characterized by two adjacent cysteines. The genes chemokine (C-C motif) ligand 14 and chemokine (C-C motif) ligand 15 are adjacent loci and express read-through transcripts spanning both loci. The read-through transcripts were originally interpreted as bicistronic transcripts, but they are represented as non-coding because they are candidates for nonsense-mediated mRNA decay (NMD). [provided by RefSeq, Dec 2009]

Known Variants1 total

rsidPosition (GRCh37)AllelesClassClinVar
rs7796127317:34,324,025C/Tupstream gene variant

Gene information from NCBI Gene. Variant classifications from ClinVar.