CCL3
C-C motif chemokine ligand 3
Summary
This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
Known Variants14 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs8951 | 17:34,415,720 | T/A | coding sequence variant | — |
| rs3210166 | 17:34,415,752 | G/C | coding sequence variant | — |
| rs1049195 | 17:34,415,765 | G/A | coding sequence variant | — |
| rs1049191 | 17:34,415,819 | G/A | coding sequence variant | — |
| rs5029407 | 17:34,415,985 | C/T | 3 prime UTR variant | — |
| rs34171309 | 17:34,416,063 | C/A | missense variant | — |
| rs773703371 | 17:34,416,094 | C/T | — | uncertain significance |
| rs5029410 | 17:34,416,151 | A/C | intron variant | — |
| rs781743526 | 17:34,416,535 | C/A | — | uncertain significance |
| rs1130374 | 17:34,416,536 | C/T | missense variant | — |
| rs1130371 | 17:34,416,537 | G/A | synonymous variant | — |
| rs771827521 | 17:34,416,559 | G/A | — | uncertain significance |
| rs764705131 | 17:34,416,599 | G/A | — | uncertain significance |
| rs35511254 | 17:34,417,292 | G/A | coding sequence variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.