CD79B

CD79b molecule

Summary

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Known Variants155 total

rsidPosition (GRCh37)AllelesClassClinVar
rs792117:62,006,259G/A3 prime UTR variant—
rs1260382117:62,006,432G/A—benign
rs105168817:62,006,433G/C—benign
rs105168417:62,006,497G/A—benign
rs214475533317:62,006,597C/T—uncertain significance
rs214475533817:62,006,598T/G—likely benign
rs78117239817:62,006,604C/T—likely benign
rs146994360017:62,006,607A/G—likely benign
rs14458893817:62,006,612C/T—uncertain significance
rs13853579017:62,006,628C/T—likely benign
rs77726634517:62,006,630C/G—uncertain significance
rs37500983417:62,006,631T/C—likely benign
rs116931444117:62,006,635C/T—uncertain significance
rs53405116717:62,006,640C/T—likely benign
rs14926649417:62,006,641G/A—uncertain significance
rs133524620417:62,006,655A/G—likely benign
rs37266511517:62,006,690G/C—likely benign
rs76654783117:62,006,778C/T—likely benign
rs37104442617:62,006,781C/T—likely benign
rs214475582917:62,006,790T/A—uncertain significance
rs19985952017:62,006,794C/T—uncertain significance
rs55909115517:62,006,796C/G—uncertain significance
rs190797785617:62,006,799A/G—likely pathogenic
rs190797808917:62,006,800G/C—likely benign
rs250926592517:62,006,801G/C—uncertain significance
rs74991700817:62,006,814C/G—uncertain significance
rs14351106717:62,006,818G/A—likely benign
rs129098943917:62,006,828C/T—uncertain significance
rs159839976917:62,006,833A/T—uncertain significance
rs74861243317:62,006,841G/A—likely benign
rs20211551417:62,006,843C/T—benign
rs19952111417:62,006,852A/G—benign
rs94624618417:62,006,854G/T—likely benign
rs989351817:62,006,997C/T—benign
rs37255376017:62,007,110T/C—likely benign
rs97893161117:62,007,113C/A—likely benign
rs20050191317:62,007,114C/T—likely benign
rs37149678917:62,007,116C/T—likely benign
rs74609529017:62,007,117G/A—likely benign
rs77230233717:62,007,119C/T—likely benign
rs116987760017:62,007,121C/G—likely benign
rs190800168417:62,007,132T/C—uncertain significance
rs190800211817:62,007,137A/T—uncertain significance
rs146299108617:62,007,145G/A—likely benign
rs14803284817:62,007,156C/T—uncertain significance
rs11509916217:62,007,157G/A—likely benign
rs214475680717:62,007,178C/T—likely benign
rs14175457217:62,007,181C/T—likely benign
rs14719482117:62,007,182G/A—uncertain significance
rs120049976117:62,007,195T/C—uncertain significance
rs128190282917:62,007,199A/T—likely benign
rs11481322817:62,007,211C/T—likely benign
rs214475691717:62,007,212G/A—uncertain significance
rs147444682217:62,007,217C/T—likely benign
rs76464596017:62,007,251G/A—likely benign
rs20105143117:62,007,252C/T—likely benign
rs55478329917:62,007,253G/A—likely benign
rs74591567417:62,007,261G/A—likely benign
rs75860110317:62,007,263G/T—likely benign
rs123458741517:62,007,266G/C—likely benign
rs190801229517:62,007,267G/A—likely benign
rs36903882117:62,007,268G/A—likely benign
rs75850370217:62,007,424T/G—likely benign
rs78019593517:62,007,426G/T—likely benign
rs74726516417:62,007,435C/T—uncertain significance
rs77773757817:62,007,442C/T—uncertain significance
rs156781005117:62,007,450T/C—conflicting classifications of pathogenicity
rs12191242417:62,007,455C/Tmissense variantpathogenic
rs74904226017:62,007,456G/A—likely benign
rs1155505817:62,007,459G/A—likely benign
rs137487897217:62,007,474C/T—likely benign
rs138955936317:62,007,475G/A—conflicting classifications of pathogenicity
rs130618030517:62,007,477G/A—likely benign
rs155559897117:62,007,483G/A—likely benign
rs37089397117:62,007,485T/C—uncertain significance
rs74543490717:62,007,492C/T—likely benign
rs207077617:62,007,498A/Gsynonymous variantbenign
rs122111858517:62,007,501G/A—likely benign
rs250926861517:62,007,502A/C—uncertain significance
rs214475772717:62,007,510G/A—likely benign
rs76040706317:62,007,513A/G—likely benign
rs190803277617:62,007,523A/C—uncertain significance
rs14723612917:62,007,526C/T—conflicting classifications of pathogenicity
rs13970782717:62,007,535T/C—uncertain significance
rs76330702217:62,007,541G/A—uncertain significance
rs156781019317:62,007,547G/A—uncertain significance
rs11662590917:62,007,552G/A—benign
rs190803692117:62,007,560C/T—uncertain significance
rs11549468517:62,007,561G/A—likely benign
rs250926883317:62,007,565T/C—uncertain significance
rs75372598917:62,007,570C/T—likely benign
rs20175774217:62,007,578T/C—uncertain significance
rs214475795117:62,007,582G/A—likely benign
rs37710818817:62,007,585C/T—likely benign
rs77963908417:62,007,592A/G—uncertain significance
rs19176165017:62,007,603C/T—likely benign
rs190804147617:62,007,608G/T—uncertain significance
rs76222621117:62,007,609A/G—likely benign
rs37308240217:62,007,614C/T—conflicting classifications of pathogenicity
rs250926900317:62,007,619A/C—uncertain significance

Showing 100 of 155 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.