CDC5L
cell division cycle 5 like
Summary
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq, Jul 2008]
Known Variants66 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs77690047 | 6:44,355,228 | A/C | — | benign |
| rs2297334 | 6:44,355,399 | G/T | — | benign |
| rs2297333 | 6:44,355,423 | C/T | — | benign |
| rs144524558 | 6:44,355,554 | C/T | — | likely benign |
| rs150971616 | 6:44,355,559 | A/G | — | likely benign |
| rs2297332 | 6:44,355,682 | G/A | — | benign |
| rs2297331 | 6:44,355,699 | T/C | — | benign |
| rs6908640 | 6:44,357,884 | T/G | — | benign |
| rs11571911 | 6:44,358,025 | G/A | — | likely benign |
| rs1016731902 | 6:44,358,106 | A/G | — | uncertain significance |
| rs9369481 | 6:44,358,444 | T/G | — | benign |
| rs7757621 | 6:44,360,155 | T/A | — | benign |
| rs778384309 | 6:44,360,465 | C/G | — | uncertain significance |
| rs556847454 | 6:44,360,491 | A/G | — | likely benign |
| rs10948136 | 6:44,360,533 | A/G | — | benign |
| rs6942323 | 6:44,360,680 | G/A | — | benign |
| rs372141515 | 6:44,361,295 | A/G | — | uncertain significance |
| rs36064417 | 6:44,361,309 | G/A | — | benign |
| rs2534991425 | 6:44,364,083 | C/T | — | uncertain significance |
| rs373544801 | 6:44,364,164 | T/C | — | likely benign |
| rs2535016484 | 6:44,371,592 | A/T | — | uncertain significance |
| rs1791245673 | 6:44,371,611 | G/A | — | uncertain significance |
| rs549734666 | 6:44,371,656 | A/C | — | uncertain significance |
| rs1561969930 | 6:44,371,704 | A/G | — | uncertain significance |
| rs6934058 | 6:44,371,714 | C/T | — | benign |
| rs79843509 | 6:44,374,056 | A/G | — | benign |
| rs534942880 | 6:44,374,076 | G/A | — | uncertain significance |
| rs1952980 | 6:44,374,467 | A/G | — | benign |
| rs1952979 | 6:44,374,508 | G/A | — | benign |
| rs6458384 | 6:44,375,919 | T/C | — | benign |
| rs377117589 | 6:44,376,171 | G/A | — | likely benign |
| rs141567880 | 6:44,376,192 | A/G | — | benign |
| rs200087867 | 6:44,376,206 | T/C | — | likely benign |
| rs376004864 | 6:44,376,302 | A/G | — | uncertain significance |
| rs144752067 | 6:44,387,233 | A/G | — | likely benign |
| rs6923521 | 6:44,387,517 | C/G | — | benign |
| rs9395016 | 6:44,387,590 | C/A | — | benign |
| rs747924598 | 6:44,390,419 | G/A | — | uncertain significance |
| rs151023284 | 6:44,390,458 | C/T | — | uncertain significance |
| rs768966403 | 6:44,390,476 | G/C | — | uncertain significance |
| rs1298525575 | 6:44,390,516 | C/G | — | uncertain significance |
| rs11572006 | 6:44,390,518 | A/G | — | benign |
| rs11572007 | 6:44,390,764 | G/T | — | benign |
| rs11572012 | 6:44,392,016 | A/C | — | benign |
| rs548309345 | 6:44,392,251 | G/A | — | likely benign |
| rs762774387 | 6:44,392,299 | T/C | — | likely benign |
| rs145762260 | 6:44,392,313 | G/A | — | uncertain significance |
| rs864127 | 6:44,392,514 | G/A | — | benign |
| rs11572020 | 6:44,393,635 | G/A | — | benign |
| rs1055398152 | 6:44,393,857 | G/T | — | uncertain significance |
| rs2532512495 | 6:44,394,313 | T/G | — | uncertain significance |
| rs368161524 | 6:44,394,370 | A/G | — | uncertain significance |
| rs777791487 | 6:44,394,421 | A/C | — | uncertain significance |
| rs11572023 | 6:44,394,422 | T/C | — | benign |
| rs4714787 | 6:44,397,281 | G/C | — | benign |
| rs2532523848 | 6:44,397,502 | A/T | — | uncertain significance |
| rs80152853 | 6:44,397,882 | T/C | — | benign |
| rs1293208 | 6:44,406,908 | A/T | — | — |
| rs11572048 | 6:44,413,460 | G/C | — | benign |
| rs2273666 | 6:44,413,463 | T/A | — | benign |
| rs1296778518 | 6:44,413,480 | G/A | — | uncertain significance |
| rs142471993 | 6:44,413,525 | T/C | — | uncertain significance |
| rs755120249 | 6:44,413,536 | C/T | — | likely benign |
| rs1295835040 | 6:44,413,548 | C/T | — | uncertain significance |
| rs202064406 | 6:44,413,549 | G/A | — | uncertain significance |
| rs2273667 | 6:44,413,736 | A/G | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.