CDCP1
CUB domain containing protein 1
Summary
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Known Variants55 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201458649 | 3:45,127,150 | G/C | — | uncertain significance |
| rs1698176388 | 3:45,127,191 | C/T | — | likely benign |
| rs1213322874 | 3:45,127,294 | C/A | — | uncertain significance |
| rs749757404 | 3:45,127,297 | T/C | — | uncertain significance |
| rs60698062 | 3:45,127,353 | C/T | — | benign |
| rs201971199 | 3:45,127,387 | C/T | — | uncertain significance |
| rs754165008 | 3:45,127,464 | C/T | — | uncertain significance |
| rs779084978 | 3:45,127,467 | C/T | — | uncertain significance |
| rs367974596 | 3:45,127,471 | T/A | — | uncertain significance |
| rs202014054 | 3:45,127,481 | T/G | — | uncertain significance |
| rs1171235882 | 3:45,127,527 | C/T | — | uncertain significance |
| rs2530736449 | 3:45,130,615 | A/G | — | uncertain significance |
| rs745729866 | 3:45,130,622 | T/C | — | likely benign |
| rs11928003 | 3:45,131,600 | G/A | intron variant | — |
| rs147957477 | 3:45,132,755 | T/C | — | uncertain significance |
| rs574793682 | 3:45,132,791 | C/T | — | uncertain significance |
| rs755865664 | 3:45,132,869 | C/T | — | uncertain significance |
| rs35353149 | 3:45,132,872 | C/T | — | benign |
| rs747034363 | 3:45,132,877 | C/T | — | uncertain significance |
| rs2530742175 | 3:45,132,906 | C/G | — | uncertain significance |
| rs763579370 | 3:45,132,911 | C/T | — | likely benign |
| rs1214607942 | 3:45,134,773 | G/T | — | uncertain significance |
| rs535446096 | 3:45,134,834 | G/C | — | uncertain significance |
| rs557036575 | 3:45,134,836 | A/T | — | uncertain significance |
| rs761817189 | 3:45,134,840 | G/T | — | uncertain significance |
| rs145437551 | 3:45,134,980 | G/T | — | uncertain significance |
| rs1470357346 | 3:45,135,005 | G/C | — | uncertain significance |
| rs368595162 | 3:45,136,998 | G/T | — | uncertain significance |
| rs1436015382 | 3:45,137,007 | C/T | — | uncertain significance |
| rs372469907 | 3:45,137,027 | C/T | — | uncertain significance |
| rs982050648 | 3:45,137,051 | T/A | — | uncertain significance |
| rs749544450 | 3:45,137,052 | A/G | — | uncertain significance |
| rs1256956002 | 3:45,152,019 | C/A | — | uncertain significance |
| rs12634943 | 3:45,152,071 | C/T | — | benign |
| rs201695787 | 3:45,152,082 | C/T | — | uncertain significance |
| rs144577185 | 3:45,152,112 | C/T | — | uncertain significance |
| rs553974292 | 3:45,152,180 | T/C | — | uncertain significance |
| rs147169827 | 3:45,152,223 | C/T | — | likely benign |
| rs139531917 | 3:45,152,297 | C/G | — | uncertain significance |
| rs35605067 | 3:45,153,051 | C/T | intron variant | — |
| rs541737948 | 3:45,153,595 | G/A | — | uncertain significance |
| rs202175025 | 3:45,153,676 | C/T | — | uncertain significance |
| rs779637766 | 3:45,153,719 | C/T | — | uncertain significance |
| rs564196123 | 3:45,153,733 | C/T | — | uncertain significance |
| rs770872061 | 3:45,153,737 | C/T | — | uncertain significance |
| rs370503753 | 3:45,153,796 | C/T | — | uncertain significance |
| rs1472471304 | 3:45,153,900 | C/G | — | uncertain significance |
| rs201301385 | 3:45,160,000 | T/C | — | uncertain significance |
| rs779842644 | 3:45,160,014 | G/A | — | uncertain significance |
| rs746389718 | 3:45,160,047 | G/A | — | uncertain significance |
| rs62242542 | 3:45,169,491 | T/C | intron variant | — |
| rs545442506 | 3:45,182,023 | C/G | — | — |
| rs185438648 | 3:45,187,200 | A/C | regulatory region variant | — |
| rs2530873780 | 3:45,187,712 | A/C | — | uncertain significance |
| rs112158839 | 3:45,187,757 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.