CFAP45
cilia and flagella associated protein 45
Summary
Enables AMP binding activity. Involved in establishment of left/right asymmetry and flagellated sperm motility. Located in axonemal microtubule and sperm flagellum. Implicated in visceral heterotaxy 11. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants54 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs750232207 | 1:159,842,313 | G/A | — | uncertain significance |
| rs2525089137 | 1:159,842,756 | T/A | — | uncertain significance |
| rs2525089145 | 1:159,842,759 | T/C | — | uncertain significance |
| rs142022446 | 1:159,842,773 | C/T | — | uncertain significance |
| rs139132888 | 1:159,842,774 | G/A | — | uncertain significance |
| rs2525089227 | 1:159,842,787 | C/G | — | uncertain significance |
| rs149683405 | 1:159,842,790 | G/A | — | likely benign |
| rs1405460234 | 1:159,842,815 | T/C | — | uncertain significance |
| rs148876212 | 1:159,842,834 | G/C | — | uncertain significance |
| rs1282420064 | 1:159,842,864 | G/T | — | uncertain significance |
| rs147644439 | 1:159,842,872 | C/G | — | uncertain significance |
| rs367766458 | 1:159,842,873 | G/A | — | uncertain significance |
| rs371893609 | 1:159,842,876 | G/A | — | uncertain significance |
| rs866030213 | 1:159,842,899 | C/T | — | uncertain significance |
| rs369393077 | 1:159,842,930 | G/A | — | uncertain significance |
| rs753000535 | 1:159,842,953 | T/C | — | uncertain significance |
| rs187171464 | 1:159,845,109 | G/A | upstream gene variant | — |
| rs77150830 | 1:159,846,372 | G/A | — | likely benign |
| rs748696479 | 1:159,846,416 | C/A | — | uncertain significance |
| rs755987678 | 1:159,846,488 | T/C | — | uncertain significance |
| rs745433119 | 1:159,846,496 | T/C | — | uncertain significance |
| rs770179632 | 1:159,846,512 | C/T | — | uncertain significance |
| rs200252683 | 1:159,846,520 | C/T | — | uncertain significance |
| rs1483238059 | 1:159,846,521 | G/T | — | uncertain significance |
| rs369854463 | 1:159,847,185 | C/A | — | uncertain significance |
| rs766373946 | 1:159,847,226 | C/A | — | uncertain significance |
| rs1229883341 | 1:159,850,365 | C/T | — | uncertain significance |
| rs145119988 | 1:159,850,375 | T/C | — | uncertain significance |
| rs1365860809 | 1:159,850,430 | C/A | — | uncertain significance |
| rs144418075 | 1:159,850,439 | G/A | — | uncertain significance |
| rs368911610 | 1:159,850,440 | C/A | — | uncertain significance |
| rs201144590 | 1:159,850,481 | G/A | — | pathogenic |
| rs1462824083 | 1:159,854,254 | A/G | — | uncertain significance |
| rs767864203 | 1:159,854,287 | C/T | — | uncertain significance |
| rs767605282 | 1:159,854,348 | G/A | — | uncertain significance |
| rs2101847449 | 1:159,856,347 | G/A | — | pathogenic |
| rs112274025 | 1:159,856,388 | C/T | — | likely benign |
| rs35975416 | 1:159,856,403 | T/C | — | benign |
| rs2501324 | 1:159,856,429 | C/T | synonymous variant | — |
| rs138866715 | 1:159,856,449 | G/A | — | uncertain significance |
| rs2525118970 | 1:159,857,666 | T/G | — | uncertain significance |
| rs371524691 | 1:159,857,668 | C/T | — | uncertain significance |
| rs776543202 | 1:159,857,704 | C/T | — | uncertain significance |
| rs1266476730 | 1:159,857,773 | A/G | — | uncertain significance |
| rs71628154 | 1:159,858,937 | T/C | — | — |
| rs760769998 | 1:159,860,292 | G/A | — | uncertain significance |
| rs750185938 | 1:159,860,321 | C/T | — | likely benign |
| rs2525125979 | 1:159,860,337 | C/T | — | uncertain significance |
| rs764217890 | 1:159,860,361 | G/T | — | uncertain significance |
| rs1292028316 | 1:159,860,372 | A/C | — | uncertain significance |
| rs780033471 | 1:159,860,373 | G/A | — | uncertain significance |
| rs755026400 | 1:159,860,385 | G/T | — | uncertain significance |
| rs372198026 | 1:159,862,974 | A/G | — | uncertain significance |
| rs544005243 | 1:159,863,056 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.